Single-player games like The Killing Antidote
Below are 14 single-player Steam games similar to The Killing Antidote, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like The Killing Antidote page.
Ranked picks
- 1
Bio Goddess : Doomsday Begins
Single-player alternative to The Killing Antidote — playable solo, no multiplayer required. Shares Action and Indie with The Killing Antidote.
Bio Goddess: Doomsday Begins is a third-person shooter survival game where players assume the role of a female high school student surviving in a school struck by a biochemical crisis. They investigate the events, uncover their connection to their father, and explore their own identity.
- 2
Morte Accendere
Single-player alternative to The Killing Antidote — playable solo, no multiplayer required. Shares Action and Indie with The Killing Antidote.
A sci-fi zombie infected third or first person action with elements of parkour, combat with weapons or hand to hand, many modes of transportation. Ability to craft items and build your safe zone.
- 3
Airtight City 密闭之城1.0
Single-player alternative to The Killing Antidote — playable solo, no multiplayer required. Shares Action and Indie with The Killing Antidote.
This is a TPS, horror-type action shooting game. The game will draw players into a terrifying dark world with detailed atmosphere rendering and weird story. Here, you are not defenseless, but even with a gun, you can't suppress the trembling from the heart. Game revenue is used for 2.0 development.
- 4
Resident Evil Revelations
Single-player alternative to The Killing Antidote — playable solo, no multiplayer required. Shares Action and Adventure with The Killing Antidote.
Resident Evil® Revelations returns redefined for PC complete with high quality HD visuals, enhanced lighting effects and an immersive sound experience.
- 5
深空七号 Deep Space 7
Single-player alternative to The Killing Antidote — playable solo, no multiplayer required. Shares Action and Indie with The Killing Antidote.
This is an independent action shooting game with a third person horror atmosphere. Facing the terrifying monsters in the space station, you must overcome the shortage of supplies, solve numerous mysteries, and successfully escape danger
- 6
Them and Us
Single-player alternative to The Killing Antidote — playable solo, no multiplayer required. Shares Action and Indie with The Killing Antidote.
Them and Us is a classic, survival horror game with a focus on atmosphere and player immersion. Discover the truth of Alicia’s past as she descends further into her strange, unending nightmare.
- 7
Resident Evil 5
Single-player alternative to The Killing Antidote — playable solo, no multiplayer required. Shares Action and Adventure with The Killing Antidote.
This game is a port of the Games for Windows - Live version that was released in 2009. If you buy the Untold Stories Bundle here on Steam, it will be the same as upgrading to Resident Evil 5 Gold Edition.
- 8
Resident Evil 4
Single-player alternative to The Killing Antidote — playable solo, no multiplayer required. Shares Action and Adventure with The Killing Antidote.
Survival is just the beginning. Six years have passed since the biological disaster in Raccoon City. Leon S. Kennedy, one of the survivors, tracks the president's kidnapped daughter to a secluded European village, where there is something terribly wrong with the locals.
- 9
Resident Evil 2
Single-player alternative to The Killing Antidote — playable solo, no multiplayer required. Shares Action with The Killing Antidote.
A deadly virus engulfs the residents of Raccoon City in September of 1998, plunging the city into chaos as flesh eating zombies roam the streets for survivors. An unparalleled adrenaline rush, gripping storyline, and unimaginable horrors await you. Witness the return of Resident Evil 2.
- 10
Resident Evil
Single-player alternative to The Killing Antidote — playable solo, no multiplayer required. Shares Action and Adventure with The Killing Antidote.
The game that defined the survival-horror genre is back! Check out the remastered HD version of Resident Evil.
- 11
Resident Evil 3
Single-player alternative to The Killing Antidote — playable solo, no multiplayer required. Shares Action with The Killing Antidote.
Jill Valentine is one of the last remaining people in Raccoon City to witness the atrocities Umbrella performed. To stop her, Umbrella unleashes their ultimate secret weapon: Nemesis! Also includes Resident Evil Resistance, a new 1 vs 4 online multiplayer game set in the Resident Evil universe.
- 12
Project Zomboid
Single-player alternative to The Killing Antidote — playable solo, no multiplayer required. Shares Indie and RPG with The Killing Antidote.
Project Zomboid is the ultimate in zombie survival. Alone or in MP: you loot, build, craft, fight, farm and fish in a struggle to survive. A hardcore RPG skillset, a vast map, massively customisable sandbox and a cute tutorial raccoon await the unwary. So how will you die? All it takes is a bite..
- 13
Stellar Blade™
Single-player alternative to The Killing Antidote — playable solo, no multiplayer required. Shares Action and Adventure with The Killing Antidote.
Save humanity from extinction in post-apocalyptic action-adventure Stellar Blade™. Experience blistering combat and a twisting storyline as you unravel the mysteries of Earth’s downfall.
- 14
The Evil Within
Single-player alternative to The Killing Antidote — playable solo, no multiplayer required. Shares Action with The Killing Antidote.
Developed by Shinji Mikami -- creator of the seminal Resident Evil series -- and the talented team at Tango Gameworks, The Evil Within embodies the meaning of pure survival horror. Highly-crafted environments, horrifying anxiety, and an intricate story are combined to create an immersive world that will bring you to the height of tension.