Single-player games like PATHOGEN X
Below are 17 single-player Steam games similar to PATHOGEN X, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like PATHOGEN X page.
Ranked picks
- 1

EBOLA VILLAGE
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action and Indie with PATHOGEN X.
EBOLA VILLAGE - this is a classic survival horror game from the 90s with a focus on atmosphere and player immersion. Solve puzzles, follow the story carefully and use various weapons in a brutal fight for survival. Danger lurks at every turn.
- 2

Connection: The Nightmare Within
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action and Adventure with PATHOGEN X.
Inspired by the classics such as Resident Evil, Silent Hill and Alone In the Dark: Detective Stone investigates a shadow conspiracy. Explore atmospheric levels, fight monsters, and solve puzzles. Unravel a story of twists and turns. Choose classic fixed camera, or over-the-shoulder.
- 3

Resident Evil 4 (2005)
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action and Adventure with PATHOGEN X.
(Release: 2014) Special agent Leon S. Kennedy is sent on a mission to rescue the U.S. President’s daughter who has been kidnapped.
- 4

ZERO PROTOCOL
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action and Adventure with PATHOGEN X.
In this immersive sci-fi thriller, you will experience the atmosphere of classic 3D games as you solve puzzles, follow an intriguing non-linear storyline, and engage in battles with monsters.
- 5

Beyond Hanwell
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action and Indie with PATHOGEN X.
Explore Westminster, London on a journey to the ruins of Hanwell. Fight with whatever you can find or use the environment to defend yourself against an ever increasing scourge of Anomalies.
- 6

Amnesia: The Dark Descent
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action and Indie with PATHOGEN X.
Amnesia: The Dark Descent, a first person survival horror. A game about immersion, discovery and living through a nightmare. An experience that will chill you to the core.
- 7

Outlast
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action and Indie with PATHOGEN X.
Hell is an experiment you can't survive in Outlast, a first-person survival horror game developed by veterans of some of the biggest game franchises in history. As investigative journalist Miles Upshur, explore Mount Massive Asylum and try to survive long enough to discover its terrible secret... if you dare.
- 8

Last Hope Bunker: Zombie Survival
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action and Indie with PATHOGEN X.
You wake up in a bunker! The Earth became a battlefield. Dangerous creatures at every turn. We give you everything you need: medicine, weapons, shelter. Your task is to find your family. And please try to survive in this post-apocalypse.
- 9

Resident Evil
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action and Adventure with PATHOGEN X.
The game that defined the survival-horror genre is back! Check out the remastered HD version of Resident Evil.
- 10

Quake
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action with PATHOGEN X.
Developed by the award-winning id Software, Quake® is the ground-breaking, original dark fantasy first-person shooter that inspires today’s retro-style FPS games. With Quake (Enhanced), experience the authentic, updated, and visually enhanced version of the original.
- 11

Unreal Tournament: Game of the Year Edition
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action with PATHOGEN X.
Unreal Tournament is the original King of the Hill in the frag-or-be-fragged multiplayer gaming world. As the undisputed 1999 Game of the Year, Unreal Tournament grabbed the first person shooter genre by the soiled seat of its pants and knocked it around the room with its never-before-seen graphics, brutal edge-of-your-seat gameplay and...
- 12

F.E.A.R. 2: Project Origin
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action with PATHOGEN X.
Assume the role of Special Forces Sgt. Becket as your routine mission quickly turns into a fight for survival against the wrath of Alma Wade. As Alma's terrifying power surges out of control, your squad is forced to battle through an apocalyptic landscape in search of clues for how to destroy her!
- 13

Serious Sam 3: BFE
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action and Indie with PATHOGEN X.
Serious Sam 3: BFE is a prequel to the original indie fast action FPS and Game of the Year sensation - Serious Sam: The First Encounter!
- 14

Resident Evil 7 Biohazard
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action and Adventure with PATHOGEN X.
Fear and isolation seep through the walls of an abandoned southern farmhouse. "7" marks a new beginning for survival horror with the “Isolated View” of the visceral new first-person perspective.
- 15

Resident Evil 2
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action with PATHOGEN X.
A deadly virus engulfs the residents of Raccoon City in September of 1998, plunging the city into chaos as flesh eating zombies roam the streets for survivors. An unparalleled adrenaline rush, gripping storyline, and unimaginable horrors await you. Witness the return of Resident Evil 2.
- 16

VLADiK BRUTAL
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action and Indie with PATHOGEN X.
Fight under the onslaught of mutated monsters, obsessed soldiers and even darker bosses. Just try to survive and find out what to do next in this life, simultaneously tearing your enemies to pieces.
- 17

OPEN DOOR
Single-player alternative to PATHOGEN X — playable solo, no multiplayer required. Shares Action and Indie with PATHOGEN X.
A scientific experiment in which no one survives, in a first-person survival horror game made by one developer In the role of a random person who is trapped in an experiment, try to get out and find out what is happening in this abandoned place.