Single-player games like Endoparasitic 2
Below are 14 single-player Steam games similar to Endoparasitic 2, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Endoparasitic 2 page.
Ranked picks
- 1

Endoparasitic
Single-player alternative to Endoparasitic 2 — playable solo, no multiplayer required. Shares Indie with Endoparasitic 2.
Three limbs ripped off, infected with a deadly parasite, you must save your research. Drag yourself through the corridors of a secret research lab on a remote asteroid, fight off horribly mutated monsters, inject countless syringes of vaccines, and survive at all costs.
- 2

EMPTY SHELL 2
Single-player alternative to Endoparasitic 2 — playable solo, no multiplayer required. Shares Action and Indie with Endoparasitic 2.
Take on the roles of expendable volunteers sent to a forsaken facility on a remote Japanese island. Recover lost data, scavenge for resources, manage your inventory, and endure unspeakable cosmic horrors. In this top-down extraction survival horror, every expedition is a journey back from madness.
- 3

the machine that BREATHES
Single-player alternative to Endoparasitic 2 — playable solo, no multiplayer required. Shares Action and Indie with Endoparasitic 2.
the machine that BREATHES is a 2D Survival Horror game with a focus on situational combat and exploration. Inspired by the likes of Resident Evil and System Shock, you'll crawl through a hostile environment and manage a limited inventory to brace against the unknown.
- 4

DERELIKT
Single-player alternative to Endoparasitic 2 — playable solo, no multiplayer required. Shares Action and Indie with Endoparasitic 2.
DERELIKT is a narrative retro FPS built for fans of claustrophobic PS1-era sci-fi horror.
- 5

Endoparasitic VR
Single-player alternative to Endoparasitic 2 — playable solo, no multiplayer required. Shares Action with Endoparasitic 2.
Three limbs ripped off, infected with a deadly parasite, you must save your research. Drag yourself through the corridors of a secret research lab on a remote asteroid, fight off horribly mutated monsters, inject countless syringes of vaccines, and survive at all costs.
- 6

Effigy : The Descent
Single-player alternative to Endoparasitic 2 — playable solo, no multiplayer required. Shares Action and Indie with Endoparasitic 2.
Effigy : The Descent is a first-person survival-horror game in which you will face statues, with your lantern as your only tool to stop them. Gather all artefacts from the cave and freedom will be yours !
- 7

Half Left
Single-player alternative to Endoparasitic 2 — playable solo, no multiplayer required. Shares Action and Indie with Endoparasitic 2.
Trapped inside a quarantined research complex, a wheelchair-bound nurse must survive a curse beyond human comprehension.
- 8

ONE SHOT OUT
Single-player alternative to Endoparasitic 2 — playable solo, no multiplayer required. Shares Action and Indie with Endoparasitic 2.
One prisoner. One hit kills you. Fight through 30 sectors of a space prison ship in a top-down roguelike shooter where every bullet can end your run. Reflexes, precision and dash — or die trying.
- 9

Voyager-19
Single-player alternative to Endoparasitic 2 — playable solo, no multiplayer required. Shares Indie with Endoparasitic 2.
A short horror game where you control a decaying spacecraft exploring distant star systems.
- 10

Wrought Flesh
Single-player alternative to Endoparasitic 2 — playable solo, no multiplayer required. Shares Action with Endoparasitic 2.
Rip out organs and equip them in your own body. Fight biopunk monsters and drugged-up space bandits. You are a Gajeshian Cultist: A near-mythological being built from the bodies of long-dead saints.
- 11

InterSection
Single-player alternative to Endoparasitic 2 — playable solo, no multiplayer required. Shares Indie with Endoparasitic 2.
InterSection is an interdimensional physics puzzle game where you exist in the intersection of two worlds and must manipulate them to pass obstacles.
- 12

Theyest Thou
Single-player alternative to Endoparasitic 2 — playable solo, no multiplayer required. Shares Action and Indie with Endoparasitic 2.
Play as a telekinetic gunslinger infiltrating a rebel base to find the deep space coordinates of kidnapped royalty and uncover a secret conspiracy.
- 13

StarPrey
Single-player alternative to Endoparasitic 2 — playable solo, no multiplayer required. Shares Action and Indie with Endoparasitic 2.
Fast-paced top-down physicsy space dogfighting action
- 14

Homauton
Single-player alternative to Endoparasitic 2 — playable solo, no multiplayer required. Shares Indie with Endoparasitic 2.
A tiny horror automation game. Trapped in a cramped landing pod with only a hibernation chamber and drone control computer, investigate the abandoned surface of a dead planet and build a rocket to escape before your family back home dies of old age.