Single-player games like Pathologic 3
Below are 13 single-player Steam games similar to Pathologic 3, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Pathologic 3 page.
Ranked picks
- 1

Pathologic 3: Quarantine
Single-player alternative to Pathologic 3 — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic 3.
In this free prologue to a narrative-driven adventure, watch a mysterious plague break out in a small town. Learn what drove a celebrated academic to leave his acclaimed lab. Examine patients, uncover strange secrets, and make first steps towards immortality.
- 2

Pathologic 2
Single-player alternative to Pathologic 3 — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic 3.
Pathologic 2 is a groundbreaking open-world horror RPG. Resist the plague. Make medicine. Heal people. Perform an autopsy. Trade to get what you need. Fight and kill if necessary. Survive. Struggle with an outbreak in a secluded rural town that is rapidly turning into hell.
- 3

Dead Take
Single-player alternative to Pathologic 3 — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic 3.
Find your missing friend. Uncover the secrets within. Brave a luxurious and haunting mansion in Dead Take, a first-person psychological horror crafted by Surgent Studios.
- 4

Static Dread: The Lighthouse
Single-player alternative to Pathologic 3 — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic 3.
Lovecraft meets Papers, Please. Play as a lighthouse keeper and guide ships safely into the harbor using your radio. Survive the presence of something impossible, and don’t let the shadows consume you!
- 5

SILENT HILL 2
Single-player alternative to Pathologic 3 — playable solo, no multiplayer required. Shares Adventure with Pathologic 3.
Investigating a letter from his late wife, James returns to where they made so many memories - Silent Hill. What he finds is a ghost town, prowled by disturbing monsters and cloaked in deep fog. Confront the monsters, solve puzzles, and search for traces of your wife in this remake of SILENT HILL 2.
- 6

Disco Elysium - The Final Cut
Single-player alternative to Pathologic 3 — playable solo, no multiplayer required. Shares RPG with Pathologic 3.
Disco Elysium - The Final Cut is a groundbreaking role playing game. You’re a detective with a unique skill system at your disposal and a whole city to carve your path across. Interrogate unforgettable characters, crack murders or take bribes. Become a hero or an absolute disaster of a human being.
- 7

Visage
Single-player alternative to Pathologic 3 — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic 3.
Visage is a first-person psychological horror game. Explore a mysterious ever-changing house in a slow-paced, atmospheric world that combines both uncannily comforting and horrifyingly realistic environments, and enjoy a genuinely terrifying experience.
- 8

Resident Evil
Single-player alternative to Pathologic 3 — playable solo, no multiplayer required. Shares Adventure with Pathologic 3.
The game that defined the survival-horror genre is back! Check out the remastered HD version of Resident Evil.
- 9

Pathologic Classic HD
Single-player alternative to Pathologic 3 — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic 3.
Pathologic Classic HD is the Definitive Edition of the original Cult Classic Psychological First-Person Survival game. In this unforgettable experience, players control one of three unique characters as they try to save a mysterious town from a deadly plague that cannot be stopped.
- 10

Knock-knock
Single-player alternative to Pathologic 3 — playable solo, no multiplayer required. Shares Adventure with Pathologic 3.
There is an unusual cabin deep in the woods. It had served as a laboratory and a dwelling for three generations of Lodgers.But as of late the latest Lodger has been noticing weird changes in familiar surroundings; things are missing, noises and rattle heard. Something odd is coming out of the woods.
- 11

The Void
Single-player alternative to Pathologic 3 — playable solo, no multiplayer required. Shares Adventure with Pathologic 3.
Only brought to life by scarce sparks of Color, the bleak, grey Void is a peculiar place. The player gets to explore it, get to know the Sisters, Brothers, and other weird creatures inhabiting it, and learn the ways of Color, harvesting it and drawing sigils that change the world around them.
- 12

Know by heart
Single-player alternative to Pathologic 3 — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic 3.
Childhood friends reunite after spending a long time apart, revisiting old memories and rekindling their friendship. However, something beyond their control will ruin this reunion.
- 13

Cargo! The Quest for Gravity
Single-player alternative to Pathologic 3 — playable solo, no multiplayer required. Shares Adventure and Simulation with Pathologic 3.
Create crazy, yet functional, custom vehicles to solve missions with your own unique style!