Single-player games like Pathologic 3: Quarantine
Below are 13 single-player Steam games similar to Pathologic 3: Quarantine, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Pathologic 3: Quarantine page.
Ranked picks
- 1
Pathologic 3
Single-player alternative to Pathologic 3: Quarantine — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic 3: Quarantine.
In this psychological horror game, you are a doctor with only 12 days to save a town from a mysterious plague. Make ruthless decisions and diagnose with precision. Shape the town's future and rewrite the past. Hold yourself together while it all falls apart.
- 2
Pathologic 2
Single-player alternative to Pathologic 3: Quarantine — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic 3: Quarantine.
Pathologic 2 is a groundbreaking open-world horror RPG. Resist the plague. Make medicine. Heal people. Perform an autopsy. Trade to get what you need. Fight and kill if necessary. Survive. Struggle with an outbreak in a secluded rural town that is rapidly turning into hell.
- 3
Penumbra: Black Plague Gold Edition
Single-player alternative to Pathologic 3: Quarantine — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic 3: Quarantine.
Surrounded by enemies and assaulted by terror from all sides, Philip must collect clues and solve vexing puzzles while combating the gnawing psychological terrors that assail his mind and threaten to strip him of his sanity.
- 4
Static Dread: The Lighthouse
Single-player alternative to Pathologic 3: Quarantine — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic 3: Quarantine.
Lovecraft meets Papers, Please. Play as a lighthouse keeper and guide ships safely into the harbor using your radio. Survive the presence of something impossible, and don’t let the shadows consume you!
- 5
Amnesia: The Dark Descent
Single-player alternative to Pathologic 3: Quarantine — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic 3: Quarantine.
Amnesia: The Dark Descent, a first person survival horror. A game about immersion, discovery and living through a nightmare. An experience that will chill you to the core.
- 6
Visage
Single-player alternative to Pathologic 3: Quarantine — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic 3: Quarantine.
Visage is a first-person psychological horror game. Explore a mysterious ever-changing house in a slow-paced, atmospheric world that combines both uncannily comforting and horrifyingly realistic environments, and enjoy a genuinely terrifying experience.
- 7
Disco Elysium - The Final Cut
Single-player alternative to Pathologic 3: Quarantine — playable solo, no multiplayer required. Shares RPG with Pathologic 3: Quarantine.
Disco Elysium - The Final Cut is a groundbreaking role playing game. You’re a detective with a unique skill system at your disposal and a whole city to carve your path across. Interrogate unforgettable characters, crack murders or take bribes. Become a hero or an absolute disaster of a human being.
- 8
Darkwood
Single-player alternative to Pathologic 3: Quarantine — playable solo, no multiplayer required. Shares Adventure and RPG with Pathologic 3: Quarantine.
Darkwood - a new perspective on survival horror. Scavenge and explore a rich, ever-changing free-roam world by day, then hunker down in your hideout and pray for the morning light.
- 9
Pathologic Classic HD
Single-player alternative to Pathologic 3: Quarantine — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic 3: Quarantine.
Pathologic Classic HD is the Definitive Edition of the original Cult Classic Psychological First-Person Survival game. In this unforgettable experience, players control one of three unique characters as they try to save a mysterious town from a deadly plague that cannot be stopped.
- 10
Knock-knock
Single-player alternative to Pathologic 3: Quarantine — playable solo, no multiplayer required. Shares Adventure with Pathologic 3: Quarantine.
There is an unusual cabin deep in the woods. It had served as a laboratory and a dwelling for three generations of Lodgers.But as of late the latest Lodger has been noticing weird changes in familiar surroundings; things are missing, noises and rattle heard. Something odd is coming out of the woods.
- 11
The Void
Single-player alternative to Pathologic 3: Quarantine — playable solo, no multiplayer required. Shares Adventure with Pathologic 3: Quarantine.
Only brought to life by scarce sparks of Color, the bleak, grey Void is a peculiar place. The player gets to explore it, get to know the Sisters, Brothers, and other weird creatures inhabiting it, and learn the ways of Color, harvesting it and drawing sigils that change the world around them.
- 12
Know by heart
Single-player alternative to Pathologic 3: Quarantine — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic 3: Quarantine.
Childhood friends reunite after spending a long time apart, revisiting old memories and rekindling their friendship. However, something beyond their control will ruin this reunion.
- 13
Cargo! The Quest for Gravity
Single-player alternative to Pathologic 3: Quarantine — playable solo, no multiplayer required. Shares Adventure and Simulation with Pathologic 3: Quarantine.
Create crazy, yet functional, custom vehicles to solve missions with your own unique style!