Single-player games like TIS-100
Below are 16 single-player Steam games similar to TIS-100, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like TIS-100 page.
Ranked picks
- 1

SHENZHEN I/O
Single-player alternative to TIS-100 — playable solo, no multiplayer required. Shares Indie and Simulation with TIS-100.
BUILD CIRCUITS. WRITE CODE. RTFM.
- 2

EXAPUNKS
Single-player alternative to TIS-100 — playable solo, no multiplayer required. Shares Indie and Simulation with TIS-100.
The year is 1997. You used to be a hacker, but now you have the phage. You made a deal: one hack, one dose. There’s nothing left to lose… except your life.
- 3

SpaceChem
Single-player alternative to TIS-100 — playable solo, no multiplayer required. Shares Indie and Simulation with TIS-100.
Zachtronics is back with an ambitious new design-based puzzle game. Take on the role of a Reactor Engineer working for SpaceChem, the leading chemical synthesizer for frontier colonies. Construct elaborate factories to transform raw materials into valuable chemical products!
- 4

Opus Magnum
Single-player alternative to TIS-100 — playable solo, no multiplayer required. Shares Indie and Simulation with TIS-100.
Opus Magnum is the latest open-ended puzzle game from Zachtronics, the creators of SpaceChem, Infinifactory, and SHENZHEN I/O. Design and build machines that assemble potions, poisons, and more using the alchemical engineer’s most advanced tool: the transmutation engine!
- 5

Escape From Hard Drive
Single-player alternative to TIS-100 — playable solo, no multiplayer required. Shares Indie and Simulation with TIS-100.
EFHD is a game where programs change how game works. Modify and run the source files to create, destroy and move other objects.
- 6

Comet 64
Single-player alternative to TIS-100 — playable solo, no multiplayer required. Shares Indie and Simulation with TIS-100.
Comet 64 is a programming puzzle game. The year is 1984. All you got is a Comet 64 home computer and the operator's manual it came with.
- 7

Human Resource Machine
Single-player alternative to TIS-100 — playable solo, no multiplayer required. Shares Indie and Simulation with TIS-100.
Program little office workers to solve puzzles. Be a good employee! The machines are coming... for your job. From the creators of World of Goo and Little Inferno.
- 8

Infinifactory
Single-player alternative to TIS-100 — playable solo, no multiplayer required. Shares Indie and Simulation with TIS-100.
Infinifactory is a sandbox puzzle game by Zachtronics, the creators of SpaceChem and Infiniminer. Build factories that assemble products for your alien overlords, and try not to die in the process.
- 9

Prime Mover
Single-player alternative to TIS-100 — playable solo, no multiplayer required. Shares Indie and Simulation with TIS-100.
Retrace the path of the Prime Mover to uncover the story of the Byte of Burden! Prime Mover is an open-ended puzzle game about designing circuit boards.
- 10

ABI-DOS
Single-player alternative to TIS-100 — playable solo, no multiplayer required. Shares Indie and Simulation with TIS-100.
Build the most advanced operating system ever created! Can you master the fictional simulation language of this mind-bending machine? Design circuits, automate UBITS (coloured mobile data blocks), and optimize your system. The Admin is always watching, and he’s not what he seems.
- 11

Factorio
Single-player alternative to TIS-100 — playable solo, no multiplayer required. Shares Indie and Simulation with TIS-100.
Factorio is a game about building and creating automated factories to produce items of increasing complexity, within an infinite 2D world. Use your imagination to design your factory, combine simple elements into ingenious structures, and finally protect it from the creatures who don't really like you.
- 12

Baba Is You
Single-player alternative to TIS-100 — playable solo, no multiplayer required. Shares Indie with TIS-100.
Baba Is You is a puzzle game where the rules you have to follow are present as blocks you can interact with. By manipulating them, you can change how the game works, repurpose things you find in the levels and cause surprising interactions!
- 13

7 Billion Humans
Single-player alternative to TIS-100 — playable solo, no multiplayer required. Shares Indie and Simulation with TIS-100.
Automate swarms of office workers to solve puzzles inside your very own parallel computer made of people. A thrilling followup to the award winning Human Resource Machine. Now with more humans!
- 14

Last Call BBS
Single-player alternative to TIS-100 — playable solo, no multiplayer required. Shares Indie and Simulation with TIS-100.
Boot up your Z5 Powerlance and dial into Last Call BBS, the last game from Zachtronics! The Barkeep’s loaded up his retro computer with a full set of puzzle games for you to download and play. No need to worry about copy protection, they’re all fully cracked and ready to enjoy!
- 15

Eliza
Single-player alternative to TIS-100 — playable solo, no multiplayer required. Shares Indie with TIS-100.
Eliza is a visual novel about an AI counseling program, the people who develop it, and the people who use it. Follow Evelyn Ishino-Aubrey as she reconnects with people from her past, gets to know the people of Seattle who use Eliza for counseling, and decides the course of her future.
- 16

The Zachtronics Solitaire Collection
Single-player alternative to TIS-100 — playable solo, no multiplayer required. Shares Indie with TIS-100.
The Zachtronics Solitaire Collection is here! Inside you will find all seven Zachtronics solitaire games, updated with new 4K graphics, plus one brand new Tarot-themed solitaire variant only available here.