Single-player games like Post Apocalypse Microbe Lab
Below are 12 single-player Steam games similar to Post Apocalypse Microbe Lab, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Post Apocalypse Microbe Lab page.
Ranked picks
- 1
Suizokukan Project
Single-player alternative to Post Apocalypse Microbe Lab — playable solo, no multiplayer required. Shares Casual with Post Apocalypse Microbe Lab.
Turn your desktop into an aquarium! Fish, collect, earn, and decorate your aquarium. Suizokukan Project makes for the perfect companion while you do menial work in your computer.
- 2
Desktop Fishing
Single-player alternative to Post Apocalypse Microbe Lab — playable solo, no multiplayer required. Shares Indie and Casual with Post Apocalypse Microbe Lab.
Desktop Fishing is a cozy idle game that sits in the corner of your screen. Go about your usual desk work (or don't) while your frog buddy catches fish, discovers new outfits, and unlocks fishing spots.
- 3
Eggo
Single-player alternative to Post Apocalypse Microbe Lab — playable solo, no multiplayer required. Shares Indie and Casual with Post Apocalypse Microbe Lab.
Raise your baby, get married, and hatch eggs with friends right on your desktop! Start with a single egg and nurture Eggo into your special companion. Let it search for treasures from different planets on your desktop and keep you company. Dress your Eggo and even date your friends'. Play with Eggo!
- 4
Cornerpond
Single-player alternative to Post Apocalypse Microbe Lab — playable solo, no multiplayer required. Shares Indie and Casual with Post Apocalypse Microbe Lab.
A chill idle-fishing desktop toy in the corner of your screen. Buy upgrades, catch rare fish, and customize your avatar at your own pace!
- 5
Idlequarium
Single-player alternative to Post Apocalypse Microbe Lab — playable solo, no multiplayer required. Shares Indie and Casual with Post Apocalypse Microbe Lab.
Idlequarium is a casual simulation game where you raise adorable little fish to earn coins, purchase decorations, and build a fully customized aquarium.The game sits anywhere on your desktop, letting you interact with your live aquarium during work or study breaks.
- 6
Black Hole Fishing
Single-player alternative to Post Apocalypse Microbe Lab — playable solo, no multiplayer required. Shares Indie and Casual with Post Apocalypse Microbe Lab.
Black Hole Fishing is an absurd incremental game about catching, breeding, and perfecting SO MANY fish. Catch a fish, optimize its traits, then stock your pond with it as you pour fish and science into an endless singularity!
- 7
Loafing Town
Single-player alternative to Post Apocalypse Microbe Lab — playable solo, no multiplayer required. Shares Indie and Casual with Post Apocalypse Microbe Lab.
A relaxing and humorous idle god simulator that stays at the bottom of your screen or on a second monitor while you do other things. With physics-based dragging interactions, it feels just like playing with desk toys.
- 8
Fantasy Aquarium
Single-player alternative to Post Apocalypse Microbe Lab — playable solo, no multiplayer required. Shares Indie and Casual with Post Apocalypse Microbe Lab.
Fantasy Aquarium offers an effortless way to enhance your gaming experience. You can nurture a diverse range of small fish with unique characteristics and construct a vibrant fantasy world from scratch, transforming mundane fish-keeping into an engaging pursuit.
- 9
Transiruby
Single-player alternative to Post Apocalypse Microbe Lab — playable solo, no multiplayer required.
Explore the mysteries of an unknown land! ”Transiruby '' is a metroidvania game where you explore the world as a cyborg protagonist named Siruby. Slash and shoot your way to reveal its hidden secrets!
- 10
Fairune Collection
Single-player alternative to Post Apocalypse Microbe Lab — playable solo, no multiplayer required.
Fairune Collection includes four games in one package – Fairune, Fairune 2, Fairune Origin and Fairune Blast!
- 11
KAMIKO
Single-player alternative to Post Apocalypse Microbe Lab — playable solo, no multiplayer required.
Wield your weapon bestowed by the gods, and open the gates between worlds!
- 12
Picontier / ピコンティア
Single-player alternative to Post Apocalypse Microbe Lab — playable solo, no multiplayer required.
"Picontier" is a story of mystery and fascinating events that occur on an island as the main character, who awakens from a long sleep on the magical island, resumes life from scratch and meets many intriguing islanders. It is a ‘slow life RPG’ that unravels and reveals surprising twists.