Single-player games like Pathogenic
Below are 8 single-player Steam games similar to Pathogenic, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Pathogenic page.
Ranked picks
- 1
SUPER DEBT
Single-player alternative to Pathogenic — playable solo, no multiplayer required. Shares Action and Indie with Pathogenic.
Money is your life in SUPER DEBT! Fight to survive with an arsenal of wildly different weapons and upgrades. In this intense and challenging Twin-Stick Bullet-Hell Roguelike everything costs money, and we mean everything!
- 2
Sundered Soul: Chains of the Undying
Single-player alternative to Pathogenic — playable solo, no multiplayer required. Shares Action and Indie with Pathogenic.
Sundered Soul: Chains of the Undying is a fast-paced twin-stick action roguelite focused on manual aiming, dodging, and skill-based combat. Choose from 9 distinct classes with unique playstyles. Fight to break an eternal curse—where every victory is earned and every mistake is lethal.
- 3
Animal Rogues
Single-player alternative to Pathogenic — playable solo, no multiplayer required. Shares Action and Indie with Pathogenic.
Animal Rogues is a dark rogue-lite dungeon crawler bullet-hell with rpg elements. You play as an animal who fights against one possessed beast after another! Discover unique interactable objects such as slot machines, dices.. Collect magical items and level up to become more and more powerful!
- 4
Wartheon
Single-player alternative to Pathogenic — playable solo, no multiplayer required. Shares Action and Indie with Pathogenic.
Wartheon is a fast-paced 2D roguelike adventure set in a world on the brink of elemental collapse. Take control of one of four unique champions to match your taste. Customize your build, master your skills, and adapt to ever-changing layouts and enemy patterns.
- 5
Another Castle
Single-player alternative to Pathogenic — playable solo, no multiplayer required. Shares Action and Indie with Pathogenic.
Sick of playing the "Damsel in Distress" Princess Peta ventures into an ever-changing Castle filled with gun wielding cult members, mysterious secrets and a whole heap of items to help boost her firepower. Another Castle is a fast-paced, challenging dungeon-crawling roguelike shooter.
- 6
HyperParasite
Single-player alternative to Pathogenic — playable solo, no multiplayer required. Shares Action and Indie with Pathogenic.
A rogue-lite twin-stick shooter/brawler that never plays the same twice. Collect and control 60 different characters as the body-snatching alien Parasite with a grudge against humanity. Fight to the top of the food chain: possess the President, push the Big Red Button and one-up the human race.
- 7
Zombie Party
Single-player alternative to Pathogenic — playable solo, no multiplayer required. Shares Action and Indie with Pathogenic.
Zombie Party is a retro rampage of fun and over-the-top action, while still giving the players a deep and engaging Action-RPG Rogue-like experience! Go on a time traveling adventure, or delve deep into procedural dungeons full of gold, loot, and secrets!
- 8
ATOMINE
Single-player alternative to Pathogenic — playable solo, no multiplayer required. Shares Action and Indie with Pathogenic.
Atomine is a twin stick procedural shooter rogue-lite set in a virtual world with minimalist design, where the player recounts on the screen the real events of STUXNET, the first weapon ever created in the form of computer virus.