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Single-player games like Pathologic Classic HD

Below are 13 single-player Steam games similar to Pathologic Classic HD, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.

Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Pathologic Classic HD page.

Ranked picks

  1. 1
    Pathologic 2 — Steam game cover

    Pathologic 2

    Single-player alternative to Pathologic Classic HD — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic Classic HD.

    Pathologic 2 is a groundbreaking open-world horror RPG. Resist the plague. Make medicine. Heal people. Perform an autopsy. Trade to get what you need. Fight and kill if necessary. Survive. Struggle with an outbreak in a secluded rural town that is rapidly turning into hell.

    2019IndieAdventureRPG34.99 USDDeck VerifiedSingle-playerSimilar games →
  2. 2
    Pathologic 3 — Steam game cover

    Pathologic 3

    Single-player alternative to Pathologic Classic HD — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic Classic HD.

    In this psychological horror game, you are a doctor with only 12 days to save a town from a mysterious plague. Make ruthless decisions and diagnose with precision. Shape the town's future and rewrite the past. Hold yourself together while it all falls apart.

    2026IndieAdventureSimulation34.99 USDDeck PlayableSingle-playerSimilar games →
  3. 3
    Darkwood — Steam game cover

    Darkwood

    Single-player alternative to Pathologic Classic HD — playable solo, no multiplayer required. Shares Action and Adventure with Pathologic Classic HD.

    Darkwood - a new perspective on survival horror. Scavenge and explore a rich, ever-changing free-roam world by day, then hunker down in your hideout and pray for the morning light.

    2017ActionStrategyAdventure19.99 USDDeck VerifiedSingle-playerSimilar games →
  4. 4
    The Void — Steam game cover

    The Void

    Single-player alternative to Pathologic Classic HD — playable solo, no multiplayer required. Shares Action and Adventure with Pathologic Classic HD.

    Only brought to life by scarce sparks of Color, the bleak, grey Void is a peculiar place. The player gets to explore it, get to know the Sisters, Brothers, and other weird creatures inhabiting it, and learn the ways of Color, harvesting it and drawing sigils that change the world around them.

    2009ActionAdventure9.99 USDSingle-playerSimilar games →
  5. 5
    Penumbra: Black Plague Gold Edition — Steam game cover

    Penumbra: Black Plague Gold Edition

    Single-player alternative to Pathologic Classic HD — playable solo, no multiplayer required. Shares Action and Indie with Pathologic Classic HD.

    Surrounded by enemies and assaulted by terror from all sides, Philip must collect clues and solve vexing puzzles while combating the gnawing psychological terrors that assail his mind and threaten to strip him of his sanity.

    2009ActionIndieAdventure9.99 USDDeck PlayableSingle-playerSimilar games →
  6. 6
    LISA: The Painful — Steam game cover

    LISA: The Painful

    Single-player alternative to Pathologic Classic HD — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic Classic HD.

    The miserable journey of a broken man...

    2014IndieAdventureRPG7.99 USDDeck PlayableSingle-playerSimilar games →
  7. 7
    Penumbra Overture — Steam game cover

    Penumbra Overture

    Single-player alternative to Pathologic Classic HD — playable solo, no multiplayer required. Shares Action and Indie with Pathologic Classic HD.

    Penumbra: Overture is a first person survival horror game, emphasizing on survival and problem solving instead of mindless violence and gore.

    2009ActionIndieAdventure9.99 USDDeck PlayableSingle-playerSimilar games →
  8. 8
    Vampire: The Masquerade - Bloodlines — Steam game cover

    Vampire: The Masquerade - Bloodlines

    Single-player alternative to Pathologic Classic HD — playable solo, no multiplayer required. Shares Action with Pathologic Classic HD.

    Vampire®: The Masquerade-Bloodlines™ delivers a new type of RPG experience-one that blends all the core elements of a traditional RPG with the graphical richness, immediacy and brutal combat of a first-person action game. The game plunges players into the dark and gritty vampire underworld of modern-day L.A. as a creature of the night.

    2007Action19.99 USDSingle-playerSimilar games →
  9. 9
    The Elder Scrolls III: Morrowind® Game of the Year Edition — Steam game cover

    The Elder Scrolls III: Morrowind® Game of the Year Edition

    Single-player alternative to Pathologic Classic HD — playable solo, no multiplayer required. Shares RPG with Pathologic Classic HD.

    The Elder Scrolls III: Morrowind® Game of the Year Edition includes Morrowind plus all of the content from the Bloodmoon and Tribunal expansions. The original Mod Construction Set is not included in this package. An epic, open-ended single-player RPG, Morrowind allows you to create and play any kind of character imaginable.

    2009RPG14.99 USDDeck PlayableSingle-playerSimilar games →
  10. 10
    Knock-knock — Steam game cover

    Knock-knock

    Single-player alternative to Pathologic Classic HD — playable solo, no multiplayer required. Shares Adventure with Pathologic Classic HD.

    There is an unusual cabin deep in the woods. It had served as a laboratory and a dwelling for three generations of Lodgers.But as of late the latest Lodger has been noticing weird changes in familiar surroundings; things are missing, noises and rattle heard. Something odd is coming out of the woods.

    2013AdventureCasual1.99 USDSingle-playerSimilar games →
  11. 11
    Know by heart — Steam game cover

    Know by heart

    Single-player alternative to Pathologic Classic HD — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic Classic HD.

    Childhood friends reunite after spending a long time apart, revisiting old memories and rekindling their friendship. However, something beyond their control will ruin this reunion.

    2022IndieAdventureCasual19.99 USDDeck VerifiedSingle-playerSimilar games →
  12. 12
    Cargo! The Quest for Gravity — Steam game cover

    Cargo! The Quest for Gravity

    Single-player alternative to Pathologic Classic HD — playable solo, no multiplayer required. Shares Action and Adventure with Pathologic Classic HD.

    Create crazy, yet functional, custom vehicles to solve missions with your own unique style!

    2011ActionAdventureSimulation9.99 USDSingle-playerSimilar games →
  13. 13
    Pathologic 3: Quarantine — Steam game cover

    Pathologic 3: Quarantine

    Single-player alternative to Pathologic Classic HD — playable solo, no multiplayer required. Shares Indie and Adventure with Pathologic Classic HD.

    In this free prologue to a narrative-driven adventure, watch a mysterious plague break out in a small town. Learn what drove a celebrated academic to leave his acclaimed lab. Examine patients, uncover strange secrets, and make first steps towards immortality.

    2025IndieAdventureSimulationFreeDeck PlayableSingle-playerSimilar games →