Single-player games like Syndrome
Below are 18 single-player Steam games similar to Syndrome, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Syndrome page.
Ranked picks
- 1
Alien: Isolation
Single-player alternative to Syndrome — playable solo, no multiplayer required. Shares Action with Syndrome.
Discover the true meaning of fear in Alien: Isolation, a survival horror set in an atmosphere of constant dread and mortal danger.
- 2
CASE: Animatronics
Single-player alternative to Syndrome — playable solo, no multiplayer required. Shares Action and Adventure with Syndrome.
CASE: Animatronics is a truly scary and challenging first-person stealth horror on PC. Control of the police department is in the hands of anonymous hacker. All exits are locked. Electricity is off. Metallic thumps are getting closer. Will you survive, Detective Bishop?
- 3
The Persistence
Single-player alternative to Syndrome — playable solo, no multiplayer required. Shares Action and Adventure with Syndrome.
Survive aboard a doomed deep space colony starship, overrun with horrific and murderous aberrations. Explore, evade and fight your way through the depths to bring the ship back to Earth. Gather resources, upgrade abilities and fabricate an arsenal of weapons in this sci-fi horror roguelite.
- 4
Dead Effect
Single-player alternative to Syndrome — playable solo, no multiplayer required. Shares Action with Syndrome.
Fight for your life in the INDIE SCI-FI FPS game fit for both casual and hard-core gamers with a passion for hunting down hordes of zombies. Prepare yourselves for the incoming nightmare!
- 5
System Shock® 2 (1999)
Single-player alternative to Syndrome — playable solo, no multiplayer required. Shares Action with Syndrome.
"Remember, it is my will that guided you here. It is my will that gave you your cybernetic implants, the only beauty in that meat you call a body. If you value that meat... you will do as I tell you." The cult classic sci-fi horror FPS-RPG has returned.
- 6
Outlast
Single-player alternative to Syndrome — playable solo, no multiplayer required. Shares Action and Adventure with Syndrome.
Hell is an experiment you can't survive in Outlast, a first-person survival horror game developed by veterans of some of the biggest game franchises in history. As investigative journalist Miles Upshur, explore Mount Massive Asylum and try to survive long enough to discover its terrible secret... if you dare.
- 7
Amnesia: The Dark Descent
Single-player alternative to Syndrome — playable solo, no multiplayer required. Shares Action and Adventure with Syndrome.
Amnesia: The Dark Descent, a first person survival horror. A game about immersion, discovery and living through a nightmare. An experience that will chill you to the core.
- 8
Metro: Last Light Redux
Single-player alternative to Syndrome — playable solo, no multiplayer required. Shares Action with Syndrome.
It is the year 2034. Beneath the ruins of post-apocalyptic Moscow, in the tunnels of the Metro, the remnants of mankind are besieged by deadly threats from outside – and within. Mutants stalk the catacombs beneath the desolate surface, and hunt amidst the poisoned skies above.
- 9
SOMA
Single-player alternative to Syndrome — playable solo, no multiplayer required. Shares Action and Adventure with Syndrome.
From the creators of Amnesia: The Dark Descent comes SOMA, a sci-fi horror game set below the waves of the Atlantic ocean. Struggle to survive a hostile world that will make you question your very existence.
- 10
System Shock
Single-player alternative to Syndrome — playable solo, no multiplayer required. Shares Action and Adventure with Syndrome.
A first-person fight to the death in the depths of space!
- 11
Resident Evil
Single-player alternative to Syndrome — playable solo, no multiplayer required. Shares Action and Adventure with Syndrome.
The game that defined the survival-horror genre is back! Check out the remastered HD version of Resident Evil.
- 12
Dead Space
Single-player alternative to Syndrome — playable solo, no multiplayer required. Shares Action and Adventure with Syndrome.
The sci-fi survival-horror classic returns, completely rebuilt to offer an even more immersive experience — including visual, audio, and gameplay improvements — while staying faithful to the original game’s thrilling vision.
- 13
Those Who Remain
Single-player alternative to Syndrome — playable solo, no multiplayer required. Shares Adventure with Syndrome.
As the lights go out, the embers of darkness are stoked in the sleepy town of Dormont. Confront uncomfortable horrors, keep your sanity in check and survive the night in this story-driven first-person psychological-thriller.
- 14
Beneath
Single-player alternative to Syndrome — playable solo, no multiplayer required. Shares Action and Adventure with Syndrome.
Beneath is a Lovecraft-inspired survival FPS. Scarce ammo, merciless enemies and a sense of the unknown combine in a 10+ hour, story-driven single player campaign, built for both veteran gamers and those seeking a challenging old school experience.
- 15
Gemini Wars
Single-player alternative to Syndrome — playable solo, no multiplayer required.
Take control of a fleet commander returned from exile, rise through the ranks of the United Space Federation forces and join an epic war across the stars.
- 16
Mechs & Mercs: Black Talons
Single-player alternative to Syndrome — playable solo, no multiplayer required. Shares Action with Syndrome.
You are the commander of the Black Talons company, currently stationed in the Oberon system. After an eventful campaign, the military Tzanar Union has overrun the planet of Genai and blocked all departure from the system: leaving you and the Black Talons stranded.
- 17
Orczz
Single-player alternative to Syndrome — playable solo, no multiplayer required.
Orczz is a fantasy tower defense game set in the fantasy Kingdom of Whiteleaf, famous for its delicious honey wine – the mead. The player controls the Knight Order of the Mug, protectors of Whiteleaf and the mead, who are once again called to defend the land against an invading horde of orcs.
- 18
Dead Stop - No Vacancy
Single-player alternative to Syndrome — playable solo, no multiplayer required. Shares Adventure with Syndrome.
One night at the Paradise Motel. One reporter who took a wrong turn. One thing certain: nobody checks out clean. A short retro horror inspired by 80s slasher films.