Single-player games like Niche - a genetics survival game
Below are 15 single-player Steam games similar to Niche - a genetics survival game, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Niche - a genetics survival game page.
Ranked picks
- 1

Folk Emerging
Single-player alternative to Niche - a genetics survival game — playable solo, no multiplayer required. Shares Strategy and Simulation with Niche - a genetics survival game.
Lead nomadic families through the Stone Age in this turn-based 4X strategy game with in-depth characters, cultures, and ecosystems. Explore the wilderness, hunt megafauna, outsmart competitors in trade & autobattler combat. Discover fire, agriculture, politics... and survive to tell the tale.
- 2

Curious Expedition 2
Single-player alternative to Niche - a genetics survival game — playable solo, no multiplayer required. Shares Strategy and Indie with Niche - a genetics survival game.
Curious Expedition 2 is a turn-based narrative roguelike set in a reimagined version of the late 19th century that uses procedural gameplay and story elements to create completely unique and epic adventures every time you play.
- 3

The Conquest of Go
Single-player alternative to Niche - a genetics survival game — playable solo, no multiplayer required. Shares Strategy and Indie with Niche - a genetics survival game.
Learn and play Go, the classic board game that has been played for thousands of years, and compete in the race to conquer the most land in the in-game world, or compete online against opponents around the real world.
- 4

SporeBloom
Single-player alternative to Niche - a genetics survival game — playable solo, no multiplayer required. Shares Strategy and Indie with Niche - a genetics survival game.
A fungi-fueled 'battle of nutrition!' Turn-based strategy inspired by mycelium networks and territory control. Produce fantastical mushrooms and expand to outgrow your rivals. Develop peacefully or parasitize your friends in multiplayer and solo play - may the fittest fungi survive!
- 5

Reus 2
Single-player alternative to Niche - a genetics survival game — playable solo, no multiplayer required. Shares Strategy and Indie with Niche - a genetics survival game.
Shape worlds with your godly titans. Make symbiotic ecosystems and inspire humanity with your creations. Their achievements unlock new possibilities. Make different planets for different human spirits, and fill the universe with life!
- 6

dotAGE
Single-player alternative to Niche - a genetics survival game — playable solo, no multiplayer required. Shares Strategy and Indie with Niche - a genetics survival game.
Village elder, help us! The Apocalypse is approaching, and we need your guidance to survive. Assign your workers and build a thriving village against the pending doom. DotAGE is the merciless survival roguelite turn-based city builder. Will you fulfill the Prophecy?
- 7

For The King
Single-player alternative to Niche - a genetics survival game — playable solo, no multiplayer required. Shares Strategy and Indie with Niche - a genetics survival game.
For The King is a strategic RPG that blends tabletop and roguelike elements in a challenging adventure that spans the realms. Set off on a single player experience or play cooperatively both online and locally.
- 8

Islantiles
Single-player alternative to Niche - a genetics survival game — playable solo, no multiplayer required. Shares Strategy and Indie with Niche - a genetics survival game.
Islantiles is a cozy but compulsive roguelike deckbuilder. Unlock powerful technology cards, shape your deck to craft game-breaking combos, and grow your settlements to glory in this ultra-satisfying roguelike!
- 9

Rain World
Single-player alternative to Niche - a genetics survival game — playable solo, no multiplayer required. Shares Indie with Niche - a genetics survival game.
You are a nomadic slugcat, both predator and prey in a broken ecosystem. Grab your spear and brave the industrial wastes, hunting enough food to survive, but be wary— other, bigger creatures have the same plan... and slugcats look delicious.
- 10

The Sims™ 4
Single-player alternative to Niche - a genetics survival game — playable solo, no multiplayer required. Shares Simulation with Niche - a genetics survival game.
Play with life and discover the possibilities. Unleash your imagination and create a world of Sims that’s wholly unique. Explore and customize every detail from Sims to homes–and much more.
- 11

Croak Crusader: Spawn of the Spore Spectre
Single-player alternative to Niche - a genetics survival game — playable solo, no multiplayer required. Shares Indie with Niche - a genetics survival game.
Embark on an odyssey into the unknown! Behold the tale of Toadman, an enigmatic being born from alien tech and the mysteries of Radiant Verde. Witness his perilous quest through treacherous jungles to confront Captain Croak in an epic showdown! Welcome to "Spawn of the Spore Spectre"!
- 12

The Wandering Village
Single-player alternative to Niche - a genetics survival game — playable solo, no multiplayer required. Shares Strategy and Simulation with Niche - a genetics survival game.
The Wandering Village is a city-building simulation game on the back of a giant, wandering creature. Build your settlement and form a symbiotic relationship with the colossus. Will you survive together in this hostile, yet beautiful post-apocalyptic world, contaminated by poisonous plants?
- 13

Dungeon Clawler
Single-player alternative to Niche - a genetics survival game — playable solo, no multiplayer required. Shares Strategy and Simulation with Niche - a genetics survival game.
Dungeon Clawler is a Roguelike Claw Machine Deckbuilder. Build your deck, grab weapons and items from the claw machine to battle enemies, discover powerful perks that create game-changing synergies and unleash crazy combos as you fight your way through the dungeon!
- 14

Nimbatus - The Space Drone Constructor
Single-player alternative to Niche - a genetics survival game — playable solo, no multiplayer required. Shares Indie and Simulation with Niche - a genetics survival game.
Command the Nimbatus and craft drones out of hundreds of different parts. Survive unknown threats in a fully destructible, procedural universe, compete against other players in different arenas or enjoy complete creative freedom in the sandbox.
- 15

Nimbatus - Drone Creator
Single-player alternative to Niche - a genetics survival game — playable solo, no multiplayer required. Shares Indie and Simulation with Niche - a genetics survival game.
Use the Nimbatus Drone Creator to construct physically simulated drones and try them out in a virtual testing environment. Do you have what it takes to become a drone engineer?