Single-player games like Bioframe Outpost
Below are 10 single-player Steam games similar to Bioframe Outpost, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Bioframe Outpost page.
Ranked picks
- 1

Omega Warp
Single-player alternative to Bioframe Outpost — playable solo, no multiplayer required. Shares Indie and Adventure with Bioframe Outpost.
Omega Warp is a sci-fi themed action-adventure, which takes place aboard an interstellar freighter. Explore, upgrade your skills and equipment, and uncover the mysteries surrounding the freighter's loss of communication with the base of operations on Earth.
- 2

Outpost Delta
Single-player alternative to Bioframe Outpost — playable solo, no multiplayer required. Shares Indie and Adventure with Bioframe Outpost.
Outpost Delta is a single player, 2-D side-scrolling sci-fi shooter for PC. Take on the role of Delta, the outpost’s emergency defense, who along with her AI companion must defend the space station against alien intruders.
- 3

Insanely Twisted Shadow Planet
Single-player alternative to Bioframe Outpost — playable solo, no multiplayer required. Shares Indie and Adventure with Bioframe Outpost.
In this Insanely Twisted, 2-D action-adventure game, explore unique environments and battle bizarre creatures.
- 4

Exophobia
Single-player alternative to Bioframe Outpost — playable solo, no multiplayer required. Shares Indie and Adventure with Bioframe Outpost.
Explore and fight your way through a crashed human spaceship infested with relentless hordes of aliens as you become more powerful with exciting weapon upgrades and powerups in this retro inspired first-person shooter.
- 5

Goodboy Galaxy
Single-player alternative to Bioframe Outpost — playable solo, no multiplayer required. Shares Indie and Adventure with Bioframe Outpost.
A vibrant sci-fi platform adventure game where you help Maxwell the dog explore unfamiliar worlds, make strange new friends and contend with mysterious forces - by jumping, shooting, slicing, shrinking, warping and drilling.
- 6

Starcom: Unknown Space
Single-player alternative to Bioframe Outpost — playable solo, no multiplayer required. Shares Indie and Adventure with Bioframe Outpost.
Starcom: Unknown Space is an action RPG of space exploration and adventure. Build your own starship while discovering an epic story in a universe of strange mysteries, alien factions and uncharted worlds.
- 7

Zexion
Single-player alternative to Bioframe Outpost — playable solo, no multiplayer required. Shares Indie and Adventure with Bioframe Outpost.
Seek out new weapons and equipment to delve deeper into the dangerous world of Cypher-X72! Be warned, you aren't the only one seeking the forbidden technology known as Zexion! It will take cunning and valor to succeed in this action-packed sci-fi adventure!
- 8

Zapling Bygone
Single-player alternative to Bioframe Outpost — playable solo, no multiplayer required. Shares Indie and Adventure with Bioframe Outpost.
Zapling Bygone is a twisted metroidvania where you murder your foes and steal their abilities by wearing their skulls and absorbing their consciousness into your hive-mind.
- 9

Outer Wilds
Single-player alternative to Bioframe Outpost — playable solo, no multiplayer required. Shares Adventure with Bioframe Outpost.
Named Game of the Year 2019 by Giant Bomb, Polygon, Eurogamer, and The Guardian, Outer Wilds is a critically-acclaimed and award-winning open world mystery about a solar system trapped in an endless time loop.
- 10

Eufloria Classic
Single-player alternative to Bioframe Outpost — playable solo, no multiplayer required. Shares Indie with Bioframe Outpost.
Before Eufloria HD (2014), there was Eufloria (2009). The long-unlisted indie classic is available once again for the 15 year anniversary. Updated to run on modern systems, with new content, features, and expanded moddability! Old school intergalactic floral warfare is BACK! (Warts and all!)