Single-player games like Quarantine
Below are 16 single-player Steam games similar to Quarantine, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Quarantine page.
Ranked picks
- 1
Plague Inc: Evolved
Single-player alternative to Quarantine — playable solo, no multiplayer required. Shares Strategy and Simulation with Quarantine.
Plague Inc: Evolved is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero' - now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself.
- 2
Corona Simulator
Single-player alternative to Quarantine — playable solo, no multiplayer required. Shares Strategy and Simulation with Quarantine.
"Corona Simulator" is a sophisticated mixture of challenging strategy game and frighteningly detailed virus simulation. As a global pandemic leader, you must skillfully manage nations' resources, make tough decisions, and impose drastic measures to combat the deadly coronavirus.
- 3
The Last Federation
Single-player alternative to Quarantine — playable solo, no multiplayer required. Shares Strategy and Simulation with Quarantine.
From the creators of AI War: Fleet Command comes an all-new grand strategy title with turn-based tactical combat, set in a deep simulation of an entire solar system and its billions of inhabitants. You are the last of a murdered race, determined to unify or destroy the 8 others.
- 4
Phantom Doctrine
Single-player alternative to Quarantine — playable solo, no multiplayer required. Shares Strategy and RPG with Quarantine.
The year is 1983. The world teeters on the verge of destruction as the Cold War tightens its icy grip. East or West: trust no one, question everything. The fate of humanity rests in your hands as you pit spy versus spy in tactical Phantom Doctrine.
- 5
The Dungeon Of Naheulbeuk: The Amulet Of Chaos
Single-player alternative to Quarantine — playable solo, no multiplayer required. Shares Strategy with Quarantine.
Step into the wacky heroic fantasy universe of the Dungeon of Naheulbeuk. Lead a team of unlikely and clumsy heroes in an epic and challenging tactical RPG. Live an adventure filled with humor, surprises and silly encounters.
- 6
Battle Brothers
Single-player alternative to Quarantine — playable solo, no multiplayer required. Shares Strategy and Simulation with Quarantine.
Lead a mercenary company in this tactical RPG set in a medieval fantasy world. Chase fame and fortune as you choose where to go, who to recruit, which contracts to pursue, and how to train and equip your men in a procedurally generated open world campaign.
- 7
Eador. Masters of the Broken World
Single-player alternative to Quarantine — playable solo, no multiplayer required. Shares Strategy and RPG with Quarantine.
Eador is a universe made of countless shards of land drifting in the Great Nothing. Each of the shards is a little world unto itself, with geography and denizens of its own. The power over the shards is bitterly contested by Masters, the immortal beings mortals believe to be gods.
- 8
Mutant Year Zero: Road to Eden
Single-player alternative to Quarantine — playable solo, no multiplayer required. Shares Strategy and RPG with Quarantine.
A tactical game combining the turn-based combat of XCOM with story, exploration, stealth, and strategy. Take control of a team of Mutants navigating a post-human Earth. Created by a team including former HITMAN leads and the designer of PAYDAY.
- 9
Pandemic: The Board Game
Single-player alternative to Quarantine — playable solo, no multiplayer required. Shares Strategy and Simulation with Quarantine.
Humanity is on the brink of extinction. As members of an elite disease control team, you’re the only thing standing in the way of the four deadly diseases spreading across the world.
- 10
Rebel Inc: Escalation
Single-player alternative to Quarantine — playable solo, no multiplayer required. Shares Strategy and Simulation with Quarantine.
A unique and deeply engaging political/military strategic simulation from the creator of Plague Inc. Balance competing civilian and military priorities and deal with a deadly insurgency in order to stabilise a war-torn country.
- 11
Pandemic Panic!
Single-player alternative to Quarantine — playable solo, no multiplayer required.
We're in lockdown and you're our only hope! Grab your blaster, ready the cure and prepare to face the virus head on in this frantic, wacky and wild hospital. Don't be fooled, this is a task for only the best out there. Think you have what it takes?
- 12
My Riding Stables: Life with Horses
Single-player alternative to Quarantine — playable solo, no multiplayer required. Shares Simulation with Quarantine.
The Riding Stables at Mill Creek are mere ruins, but you are about to change that: stables, riding hall and guesthouse are being renovated and guests will happily pay for their stay...
- 13
Panzer Tactics HD
Single-player alternative to Quarantine — playable solo, no multiplayer required. Shares Strategy and Simulation with Quarantine.
Strategists to the frontline!The HD remake of the Nintendo DS classic.Are you the strategist that the world has been waiting for?
- 14
Riding Star - Horse Championship!
Single-player alternative to Quarantine — playable solo, no multiplayer required. Shares Simulation with Quarantine.
Ride like a world champion! Breathtaking action, challenges in show jumping, dressage and cross country riding are waiting for your talent.
- 15
My Best Friends - Cats & Dogs
Single-player alternative to Quarantine — playable solo, no multiplayer required. Shares Simulation with Quarantine.
You are responsible for the sensitive upbringing of your pet: You decide on the food, the composition of training courses, the grooming and decorating.
- 16
My Vet Practice
Single-player alternative to Quarantine — playable solo, no multiplayer required. Shares Simulation with Quarantine.
Do you sometimes dream of being a vet doctor? Now you can make that dream come true – start your own vet practice!