Single-player games like Mewgenics
Below are 22 single-player Steam games similar to Mewgenics, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Mewgenics page.
Ranked picks
- 1

Mars Tactics
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Simulation with Mewgenics.
The Red Planet is at war. Lead either Capital’s corporate army or Labor’s worker revolutionaries and wage war across a vast strategic map, then assume direct control in turn-based tactical battles featuring artillery, vehicles, and fully-destructible environments.
- 2

Pathbreakers: Roaming Blades
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Adventure with Mewgenics.
Pathbreakers: Roaming Blades is a turn-based tactical RPG where you lead a company of mercenaries in a medieval fantasy world. Try your hand at mercenary work, trading, or exploring, and keep your crew well stocked for brutal combat in a procedurally-generated open-world campaign.
- 3

TROOOPS!
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy with Mewgenics.
TROOOPS, UNITE! The Kroooken has torn apart our archipelago once more, scattering awful creatures, capturing our tribes and devouring our treasures! Only together can we bring harmony back to our seas! PREPARE TO ENGAGE!
- 4

Darkest Darkness
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Indie with Mewgenics.
Darkest Darkness is a roguelike deck-building game with extraction elements. Choose your identity and venture into a Lovecraftian town. Craft every card yourself—collect materials, build powerful cards, plan your route, or extract with your gathered materials to gain an edge in your next run.
- 5

INFERIUS
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Indie with Mewgenics.
A blend of Dante’s Inferno and Lovecraftian horror. A first-person roguelike deckbuilder using the Major Arcana Tarot Cards to strategize against the horrors lurking in the darkness. Build the perfect deck, challenge each ruler of the 9 levels of hell, die often... and repeat.
- 6

Mushroom Musume
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Indie and Adventure with Mewgenics.
Raise a mushroom from a spore into a fine young woman, then discover the twists and turns her life may take in this creepy-cute fairytale life simulation game.
- 7

As We Descend
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Indie with Mewgenics.
The apocalyptic roguelike deckbuilder with squad sculpting and deep tactics. Recruit the right units and outmaneuver titanic foes on dangerous expeditions. Build up allies and resources in the feudal Vault-City. Can you survive all the perils that await the last bastion of humanity?
- 8

The Royal Writ
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy with Mewgenics.
Sacrifice creates stories in this medieval roguelike deckbuilder. Watch your cards march to glory or permanent death as they battle toward the enemy. Each fallen hero becomes part of your kingdom's legend. Command wisely... some sacrifices are necessary.
- 9

Darkest Dungeon®
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Indie with Mewgenics.
Darkest Dungeon is a challenging gothic roguelike turn-based RPG about the psychological stresses of adventuring. Recruit, train, and lead a team of flawed heroes against unimaginable horrors, stress, disease, and the ever-encroaching dark. Can you keep your heroes together when all hope is lost?
- 10

Othercide
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Indie with Mewgenics.
As Humanity’s last hope, lead your army to combat in an intricate dance of spectacular actions and counters, using an original Dynamic Timeline System, and face fearsome bosses in epic battles.
- 11

The Binding of Isaac
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Indie and Adventure with Mewgenics.
Now 20% More Evil with the Free Halloween update!
- 12

XCOM® 2
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy with Mewgenics.
XCOM 2 is the sequel to XCOM: Enemy Unknown, the 2012 award-winning strategy game of the year. Earth has changed and is now under alien rule. Facing impossible odds you must rebuild XCOM, and ignite a global resistance to reclaim our world and save humanity.
- 13

Cult of the Lamb
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Indie with Mewgenics.
Start your own cult in a land of false prophets, venturing out into diverse and mysterious regions to build a loyal community of woodland Followers and spread your Word to become the one true cult.
- 14

Wildermyth
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Indie with Mewgenics.
Wildermyth follows heroes over their whole careers, from their pitchfork days to their powerful primes, and on into old age and memory. It’s a party-based procedural storytelling RPG where tactical combat and story decisions will alter your world and reshape your cast of characters.
- 15

Into the Breach
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Indie with Mewgenics.
Control powerful mechs from the future to defeat an alien threat. Each attempt to save the world presents a new randomly generated challenge in this turn-based strategy game.
- 16

The Hundred Line -Last Defense Academy-
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Adventure and Simulation with Mewgenics.
Kazutaka Kodaka and Kotaro Uchikoshi join forces for the first time to deliver the ULTIMATE adventure game! 15 students are tasked with defending a school from grotesque monsters for 100 days. Can they make it to the end? And will they survive long enough to uncover the truth?
- 17

The Binding of Isaac: Rebirth
Single-player alternative to Mewgenics — playable solo, no multiplayer required.
The Binding of Isaac: Rebirth is a randomly generated action RPG shooter with heavy Rogue-like elements. Following Isaac on his journey players will find bizarre treasures that change Isaac’s form giving him super human abilities and enabling him to fight off droves of mysterious creatures, discover secrets and fight his way to safety.
- 18

The Legend of Bum-Bo
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Indie with Mewgenics.
A puzzle based deck building rogue-like prequel to The Binding of Isaac... Made of cardboard!
- 19

The End Is Nigh
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Indie and Adventure with Mewgenics.
The End Is Nigh is a sprawling adventure platformer where you die a lot, but thats ok because you are probably already dead anyway.
- 20

The Basement Collection
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Indie with Mewgenics.
A collection of 9 award winning indie games from the creator of "Binding of isaac" and "Super Meat Boy"!
- 21

Fingered
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Indie with Mewgenics.
GUILTY! THEY ARE ALL GUILTY! FINGERED is a "whodunit" hyperrealisic police sim where you must finger the guilty and clean up this darn city using the descriptions of the local busy bodies. but everyone's perspective is different: one man's fat is another man's sexy! send him to the chair!!!
- 22

Gish
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Indie and Adventure with Mewgenics.
Gish isn't your average hero. In fact, he's not your average anything...you see, Gish is a ball of tar. A Sunday stroll with his lady friend, Brea, goes awry when a shadowy figure emerges from an open manhole and pulls Brea below ground.