Single-player games like Mewgenics
Below are 22 single-player Steam games similar to Mewgenics, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Mewgenics page.
Ranked picks
- 1

XCOM® 2
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy with Mewgenics.
XCOM 2 is the sequel to XCOM: Enemy Unknown, the 2012 award-winning strategy game of the year. Earth has changed and is now under alien rule. Facing impossible odds you must rebuild XCOM, and ignite a global resistance to reclaim our world and save humanity.
- 2

Into the Breach
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Indie with Mewgenics.
Control powerful mechs from the future to defeat an alien threat. Each attempt to save the world presents a new randomly generated challenge in this turn-based strategy game.
- 3

The Last Spell
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Indie and RPG with Mewgenics.
Defend the last bastion of humanity with your squad of heroes! Exterminate fiendish monsters with magic and brute force by night and re-build your battered city defenses by day in this tactical RPG with rogue-lite mechanics.
- 4

Griftlands
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Indie with Mewgenics.
Griftlands is a deck-building roguelite where you negotiate, fight, steal or otherwise persuade others to get your way. Every decision is important, be it the jobs you take, the friends you make, or the cards you collect.
- 5

Tactics Ogre: Reborn
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Simulation and RPG with Mewgenics.
Tactics Ogre, crown jewel of the tactical role-playing genre, is reborn! Based on the 2010 release, the game features improved graphics and sound, as well as updated game design, bringing to life a new Tactics Ogre that remains true to its roots.
- 6

Mutant Year Zero: Road to Eden
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares RPG and Strategy with Mewgenics.
A tactical game combining the turn-based combat of XCOM with story, exploration, stealth, and strategy. Take control of a team of Mutants navigating a post-human Earth. Created by a team including former HITMAN leads and the designer of PAYDAY.
- 7

Warhammer 40,000: Mechanicus
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy with Mewgenics.
MECHANICUS II ANNOUNCED! Take control of one of the most technologically advanced factions in the Imperium: the Adeptus Mechanicus. In this turn-based tactical game, your every decision will weigh heavily on the outcome of the conflict. Will you be blessed by the Omnissiah?
- 8

Cyber Knights: Flashpoint
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Indie and RPG with Mewgenics.
Cyberpunk mercenaries RPG! Turn-based squad tactics with unique heist-planning strategy. Build your crew wisely; their stories will become interwoven with your own. Pull off heists with powerful cyberware, faction connections, multiclassing, weapon modding, stealth, hacking, and more!
- 9

Darkest Dungeon®
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Indie with Mewgenics.
Darkest Dungeon is a challenging gothic roguelike turn-based RPG about the psychological stresses of adventuring. Recruit, train, and lead a team of flawed heroes against unimaginable horrors, stress, disease, and the ever-encroaching dark. Can you keep your heroes together when all hope is lost?
- 10

Othercide
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Indie and Strategy with Mewgenics.
As Humanity’s last hope, lead your army to combat in an intricate dance of spectacular actions and counters, using an original Dynamic Timeline System, and face fearsome bosses in epic battles.
- 11

Cult of the Lamb
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Indie with Mewgenics.
Start your own cult in a land of false prophets, venturing out into diverse and mysterious regions to build a loyal community of woodland Followers and spread your Word to become the one true cult.
- 12

Wildermyth
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Indie and RPG with Mewgenics.
Wildermyth follows heroes over their whole careers, from their pitchfork days to their powerful primes, and on into old age and memory. It’s a party-based procedural storytelling RPG where tactical combat and story decisions will alter your world and reshape your cast of characters.
- 13

The Hundred Line -Last Defense Academy-
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Adventure and Simulation with Mewgenics.
Kazutaka Kodaka and Kotaro Uchikoshi join forces for the first time to deliver the ULTIMATE adventure game! 15 students are tasked with defending a school from grotesque monsters for 100 days. Can they make it to the end? And will they survive long enough to uncover the truth?
- 14

Kenshi
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Indie with Mewgenics.
A free-roaming squad based RPG. Focusing on open-ended sandbox gameplay features rather than a linear story. Be a trader, a thief, a rebel, a warlord, an adventurer, a farmer, a slave, or just food for the cannibals. Train your men up from puny victims to master warriors.
- 15

Project Zomboid
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Indie and Simulation with Mewgenics.
Project Zomboid is the ultimate in zombie survival. Alone or in MP: you loot, build, craft, fight, farm and fish in a struggle to survive. A hardcore RPG skillset, a vast map, massively customisable sandbox and a cute tutorial raccoon await the unwary. So how will you die? All it takes is a bite..
- 16

The Binding of Isaac: Rebirth
Single-player alternative to Mewgenics — playable solo, no multiplayer required.
The Binding of Isaac: Rebirth is a randomly generated action RPG shooter with heavy Rogue-like elements. Following Isaac on his journey players will find bizarre treasures that change Isaac’s form giving him super human abilities and enabling him to fight off droves of mysterious creatures, discover secrets and fight his way to safety.
- 17

The Binding of Isaac
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Indie and Adventure with Mewgenics.
Now 20% More Evil with the Free Halloween update!
- 18

The Legend of Bum-Bo
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Adventure and Indie with Mewgenics.
A puzzle based deck building rogue-like prequel to The Binding of Isaac... Made of cardboard!
- 19

The End Is Nigh
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Indie and Adventure with Mewgenics.
The End Is Nigh is a sprawling adventure platformer where you die a lot, but thats ok because you are probably already dead anyway.
- 20

The Basement Collection
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Strategy and Indie with Mewgenics.
A collection of 9 award winning indie games from the creator of "Binding of isaac" and "Super Meat Boy"!
- 21

Fingered
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Indie with Mewgenics.
GUILTY! THEY ARE ALL GUILTY! FINGERED is a "whodunit" hyperrealisic police sim where you must finger the guilty and clean up this darn city using the descriptions of the local busy bodies. but everyone's perspective is different: one man's fat is another man's sexy! send him to the chair!!!
- 22

Gish
Single-player alternative to Mewgenics — playable solo, no multiplayer required. Shares Indie and Adventure with Mewgenics.
Gish isn't your average hero. In fact, he's not your average anything...you see, Gish is a ball of tar. A Sunday stroll with his lady friend, Brea, goes awry when a shadowy figure emerges from an open manhole and pulls Brea below ground.