Single-player games like Protolife
Below are 10 single-player Steam games similar to Protolife, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Protolife page.
Ranked picks
- 1
Revenge of the Titans
Single-player alternative to Protolife — playable solo, no multiplayer required. Shares Strategy and Indie with Protolife.
The ultimate mash-up of Real-time Strategy and Tower Defense!
- 2
Creeper World 3: Arc Eternal
Single-player alternative to Protolife — playable solo, no multiplayer required. Shares Strategy and Indie with Protolife.
Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.
- 3
Infested Planet
Single-player alternative to Protolife — playable solo, no multiplayer required. Shares Strategy and Indie with Protolife.
Command a team of 5 elite soldiers against an alien horde of 100,000. Surrounded on all sides, you must outmaneuver and outsmart the enemy.
- 4
Anomaly: Warzone Earth
Single-player alternative to Protolife — playable solo, no multiplayer required. Shares Strategy and Indie with Protolife.
Lead an armored squad through the perils of this reversed tower defense action-strategy game!
- 5
CARNAGE OFFERING Tower Defense
Single-player alternative to Protolife — playable solo, no multiplayer required. Shares Strategy and Indie with Protolife.
The replicator robots are back! It's 2528. The machines are increasingly infecting the planets with genetically modified monsters. Challenge them and try to stop the onslaught. Upgrade buildings and heroes, mine resources, discover technology and fight to save humanity!
- 6
Aliens: Dark Descent
Single-player alternative to Protolife — playable solo, no multiplayer required. Shares Strategy with Protolife.
Drop into the gripping journey of Aliens: Dark Descent, a squad-based, single-player action game in the iconic Alien franchise. Lead your soldiers in real-time to stop a new and terrifying kind of Xenomorph outbreak on Planet Lethe.
- 7
DG2: Defense Grid 2
Single-player alternative to Protolife — playable solo, no multiplayer required. Shares Strategy and Indie with Protolife.
Great strategy is timeless. Build, adapt, and defend across dynamic maps, solo or online - every session brings new strategies, new solutions, and new surprises. Now is the perfect time to enter the grid.
- 8
Grey Goo
Single-player alternative to Protolife — playable solo, no multiplayer required. Shares Strategy with Protolife.
Fight for control of a frontier world. Gather resources, build your base, and command your forces in battle. Survive long enough to unleash your ultimate weapon - THE EPIC.
- 9
Creeper World 4
Single-player alternative to Protolife — playable solo, no multiplayer required. Shares Strategy and Indie with Protolife.
The unstoppable fluid enemy has returned and destroyed every world in its path! Defend against Creeper as it floods across the 3D terrain in this real time strategy game where the enemy is a fluid.
- 10
Hexworld
Single-player alternative to Protolife — playable solo, no multiplayer required. Shares Strategy and Indie with Protolife.
Hexworld is a tactical autobattle RTS where you control the travelling kingdom-island, manage your tiles, collect and upgrade buildings, crash into other islands and watch your rare precious giant golem inevitably fall off the cliff on his way to the front lines.