Games like MOLEK-SYNTEZ
If MOLEK-SYNTEZ is your kind of game, the closest matches are Opus Magnum, SpaceChem and SHENZHEN I/O — picked from the ranked list below. Reviewers single out its atmospheric, bleak and contemplative. Each pick is ranked by what players of this game also play, shared genres and tags, and review-mined similarity — not a generic popularity list.
Get personalized picks →About MOLEK-SYNTEZ: Use the MOLEK-SYNTEZ to create small molecules with various pharmacological effects from the comfort of your small Romanian apartment.

Players who liked MOLEK-SYNTEZ also play
Steam players who put hours into MOLEK-SYNTEZ also tend to own these titles — a signal called collaborative filtering. imho.run cross-references millions of library ownership patterns to surface games whose real audiences overlap, regardless of whether their genre tags match.
Opus Magnum
WHY THIS
Shares a contemplative mood with MOLEK-SYNTEZ.
Top pick for MOLEK-SYNTEZ fans by collaborative filtering across millions of Steam libraries. Shares Indie and Simulation with MOLEK-SYNTEZ.
Opus Magnum is the latest open-ended puzzle game from Zachtronics, the creators of SpaceChem, Infinifactory, and SHENZHEN I/O. Design and build machines that assemble potions, poisons, and more using the alchemical engineer’s most advanced tool: the transmutation engine!
SpaceChem
WHY THIS
Shares a contemplative mood with MOLEK-SYNTEZ.
Second-strongest match for MOLEK-SYNTEZ fans by collaborative filtering across millions of Steam libraries. Shares Indie and Simulation with MOLEK-SYNTEZ.
Zachtronics is back with an ambitious new design-based puzzle game. Take on the role of a Reactor Engineer working for SpaceChem, the leading chemical synthesizer for frontier colonies. Construct elaborate factories to transform raw materials into valuable chemical products!
SHENZHEN I/O
WHY THIS
Shares a contemplative mood with MOLEK-SYNTEZ.
Third-strongest match for MOLEK-SYNTEZ fans by collaborative filtering across millions of Steam libraries. Shares Indie and Simulation with MOLEK-SYNTEZ.
BUILD CIRCUITS. WRITE CODE. RTFM.
EXAPUNKS
WHY THIS
Shares an atmospheric mood with MOLEK-SYNTEZ.
Ranked #4 for MOLEK-SYNTEZ fans by collaborative filtering across millions of Steam libraries. Shares Indie and Simulation with MOLEK-SYNTEZ.
The year is 1997. You used to be a hacker, but now you have the phage. You made a deal: one hack, one dose. There’s nothing left to lose… except your life.
TIS-100
WHY THIS
Ranked #5 for MOLEK-SYNTEZ fans by collaborative filtering across millions of Steam libraries. Shares Indie and Simulation with MOLEK-SYNTEZ.
TIS-100 is an open-ended programming game by Zachtronics, the creators of SpaceChem and Infinifactory, in which you rewrite corrupted code segments to repair the TIS-100 and unlock its secrets. It’s the assembly language programming game you never asked for!
Comet 64
WHY THIS
Shares an atmospheric mood with MOLEK-SYNTEZ.
Ranked #6 for MOLEK-SYNTEZ fans by collaborative filtering across millions of Steam libraries. Shares Indie and Simulation with MOLEK-SYNTEZ.
Comet 64 is a programming puzzle game. The year is 1984. All you got is a Comet 64 home computer and the operator's manual it came with.
Kaizen: A Factory Story
WHY THIS
Shares an atmospheric mood with MOLEK-SYNTEZ.
Ranked #7 for MOLEK-SYNTEZ fans by collaborative filtering across millions of Steam libraries. Shares Simulation with MOLEK-SYNTEZ.
Kaizen is an open-ended puzzle automation game from the original Zachtronics team, set in 1980s Japan. Design, build, and optimize production lines to create iconic products, like calculators, camcorders, and arcade machines.
Infinifactory
WHY THIS
Ranked #8 for MOLEK-SYNTEZ fans by collaborative filtering across millions of Steam libraries. Shares Indie and Simulation with MOLEK-SYNTEZ.
Infinifactory is a sandbox puzzle game by Zachtronics, the creators of SpaceChem and Infiniminer. Build factories that assemble products for your alien overlords, and try not to die in the process.
Reviewers mention these as similar to MOLEK-SYNTEZ
Surfaced from review text: when other players write 'if you liked X, try Y', we catch the name and resolve it back to a Steam game.
TIS-100
WHY THIS
Reviewers of MOLEK-SYNTEZ cross-mention this title as a similar play. Shares Indie and Simulation with MOLEK-SYNTEZ.
TIS-100 is an open-ended programming game by Zachtronics, the creators of SpaceChem and Infinifactory, in which you rewrite corrupted code segments to repair the TIS-100 and unlock its secrets. It’s the assembly language programming game you never asked for!
SHENZHEN I/O
WHY THIS
Shares a contemplative mood with MOLEK-SYNTEZ.
Reviewers of MOLEK-SYNTEZ cross-mention this title as a similar play. Shares Indie and Simulation with MOLEK-SYNTEZ.
BUILD CIRCUITS. WRITE CODE. RTFM.
Opus Magnum
WHY THIS
Shares a contemplative mood with MOLEK-SYNTEZ.
Reviewers of MOLEK-SYNTEZ cross-mention this title as a similar play. Shares Indie and Simulation with MOLEK-SYNTEZ.
Opus Magnum is the latest open-ended puzzle game from Zachtronics, the creators of SpaceChem, Infinifactory, and SHENZHEN I/O. Design and build machines that assemble potions, poisons, and more using the alchemical engineer’s most advanced tool: the transmutation engine!
SpaceChem
WHY THIS
Shares a contemplative mood with MOLEK-SYNTEZ.
Reviewers of MOLEK-SYNTEZ cross-mention this title as a similar play. Shares Indie and Simulation with MOLEK-SYNTEZ.
Zachtronics is back with an ambitious new design-based puzzle game. Take on the role of a Reactor Engineer working for SpaceChem, the leading chemical synthesizer for frontier colonies. Construct elaborate factories to transform raw materials into valuable chemical products!
EXAPUNKS
WHY THIS
Shares an atmospheric mood with MOLEK-SYNTEZ.
Reviewers of MOLEK-SYNTEZ cross-mention this title as a similar play. Shares Indie and Simulation with MOLEK-SYNTEZ.
The year is 1997. You used to be a hacker, but now you have the phage. You made a deal: one hack, one dose. There’s nothing left to lose… except your life.
Cheaper alternatives
Games in the same vein priced at least 40% below MOLEK-SYNTEZ at current Steam store prices.
Garry's Mod
WHY THIS
Priced ~50% under MOLEK-SYNTEZ on Steam right now. Shares Indie and Simulation with MOLEK-SYNTEZ.
Garry's Mod is a physics sandbox. There aren't any predefined aims or goals. We give you the tools and leave you to play.
Vampire Survivors
WHY THIS
Priced ~50% under MOLEK-SYNTEZ on Steam right now. Shares Indie with MOLEK-SYNTEZ.
Mow down thousands of night creatures and survive until dawn! Vampire Survivors is a gothic horror casual game with rogue-lite elements, where your choices can allow you to quickly snowball against the hundreds of monsters that get thrown at you. Be the bullet hell!
Cookie Clicker
WHY THIS
Priced ~50% under MOLEK-SYNTEZ on Steam right now. Shares Indie and Simulation with MOLEK-SYNTEZ.
An idle game about making cookies! Originally released in 2013 on the web, and actively developed since then. This is the official version for Steam.
WEBFISHING
WHY THIS
Priced ~50% under MOLEK-SYNTEZ on Steam right now. Shares Indie with MOLEK-SYNTEZ.
WEBFISHING a multiplayer chatroom-focused fishing game! Relax and fish (on the web!)
POSTAL 2
WHY THIS
Priced ~90% under MOLEK-SYNTEZ on Steam right now. Shares Indie with MOLEK-SYNTEZ.
Live a week in the life of "The POSTAL Dude"; a hapless everyman just trying to check off some chores. Buying milk, returning an overdue library book, getting Gary Coleman's autograph, what could possibly go wrong?
Buckshot Roulette
WHY THIS
Priced ~70% under MOLEK-SYNTEZ on Steam right now. Shares Indie and Simulation with MOLEK-SYNTEZ.
Play Russian roulette with a 12-gauge shotgun. Four enter. One leaves. Roll the dice with your life. Good luck!
Brotato
WHY THIS
Priced ~50% under MOLEK-SYNTEZ on Steam right now. Shares Indie with MOLEK-SYNTEZ.
Brotato is a top-down arena shooter roguelite where you play a potato wielding up to 6 weapons at a time to fight off hordes of aliens. Choose from a variety of traits and items to create unique builds and survive until help arrives.
Your Only Move Is HUSTLE
WHY THIS
Priced ~50% under MOLEK-SYNTEZ on Steam right now. Shares Indie and Simulation with MOLEK-SYNTEZ.
Master your technique, execute flashy combos, and outsmart opponents across the world, frame-by-frame. Slow down the clock to fine-tune your fighting style in this innovative, turn-based combat simulator. Pulverize your friends and choreograph spectacular fight scenes. No training mode required.
Free alternatives
Free-to-play games that recommended players of this title also tend to enjoy.
Steam Engine Simulator
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Simulation with MOLEK-SYNTEZ.
The Steam Engine Simulator shown on AngeTheGreat's YouTube channel.
last seen online
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie and Simulation with MOLEK-SYNTEZ.
Look through someone else’s computer. Inspired by early “escape room” flash games.
Jigsaw Puzzle Dreams
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with MOLEK-SYNTEZ.
Beautiful Multiplayer Jigsaw Puzzle game where you can design the room you play in!
Learn to Fly 3
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with MOLEK-SYNTEZ.
Build your spaceship from scratch, earn funds and invest them into building a bigger, better spaceship as you try and fly your way up to space!
World of Guns: Gun Disassembly
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie and Simulation with MOLEK-SYNTEZ.
World of Guns: Gun Disassembly lets you delve into the inner workings of guns from the largest gears to the smallest screws
Revolution Idle
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie and Simulation with MOLEK-SYNTEZ.
Join an experience where each revolution takes you further into the unknown! Revolution Idle challenges you to multiply your accumulators to reach unimaginable heights. Will you manage to reach infinity?
Viridi
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie and Simulation with MOLEK-SYNTEZ.
Nurture a small pot of succulents that grow in real time. Viridi is a safe haven, a place you can return to for a moment of peace and quiet whenever you need it.
Narrow it down
Head-to-head comparisons
More from Zachtronics
Other recommendable Steam games by Zachtronics, ranked by review count so the studio's hits land first.
Opus Magnum
WHY THIS
Shares a contemplative mood with MOLEK-SYNTEZ.
Another title from Zachtronics, the studio behind MOLEK-SYNTEZ. Shares Indie and Simulation with MOLEK-SYNTEZ.
Opus Magnum is the latest open-ended puzzle game from Zachtronics, the creators of SpaceChem, Infinifactory, and SHENZHEN I/O. Design and build machines that assemble potions, poisons, and more using the alchemical engineer’s most advanced tool: the transmutation engine!
SHENZHEN I/O
WHY THIS
Shares a contemplative mood with MOLEK-SYNTEZ.
Another title from Zachtronics, the studio behind MOLEK-SYNTEZ. Shares Indie and Simulation with MOLEK-SYNTEZ.
BUILD CIRCUITS. WRITE CODE. RTFM.
TIS-100
WHY THIS
Another title from Zachtronics, the studio behind MOLEK-SYNTEZ. Shares Indie and Simulation with MOLEK-SYNTEZ.
TIS-100 is an open-ended programming game by Zachtronics, the creators of SpaceChem and Infinifactory, in which you rewrite corrupted code segments to repair the TIS-100 and unlock its secrets. It’s the assembly language programming game you never asked for!
SpaceChem
WHY THIS
Shares a contemplative mood with MOLEK-SYNTEZ.
Another title from Zachtronics, the studio behind MOLEK-SYNTEZ. Shares Indie and Simulation with MOLEK-SYNTEZ.
Zachtronics is back with an ambitious new design-based puzzle game. Take on the role of a Reactor Engineer working for SpaceChem, the leading chemical synthesizer for frontier colonies. Construct elaborate factories to transform raw materials into valuable chemical products!
Infinifactory
WHY THIS
Another title from Zachtronics, the studio behind MOLEK-SYNTEZ. Shares Indie and Simulation with MOLEK-SYNTEZ.
Infinifactory is a sandbox puzzle game by Zachtronics, the creators of SpaceChem and Infiniminer. Build factories that assemble products for your alien overlords, and try not to die in the process.
EXAPUNKS
WHY THIS
Shares an atmospheric mood with MOLEK-SYNTEZ.
Another title from Zachtronics, the studio behind MOLEK-SYNTEZ. Shares Indie and Simulation with MOLEK-SYNTEZ.
The year is 1997. You used to be a hacker, but now you have the phage. You made a deal: one hack, one dose. There’s nothing left to lose… except your life.
Last Call BBS
WHY THIS
Shares an atmospheric mood with MOLEK-SYNTEZ.
Another title from Zachtronics, the studio behind MOLEK-SYNTEZ. Shares Indie and Simulation with MOLEK-SYNTEZ.
Boot up your Z5 Powerlance and dial into Last Call BBS, the last game from Zachtronics! The Barkeep’s loaded up his retro computer with a full set of puzzle games for you to download and play. No need to worry about copy protection, they’re all fully cracked and ready to enjoy!
Eliza
WHY THIS
Shares an atmospheric mood with MOLEK-SYNTEZ.
Another title from Zachtronics, the studio behind MOLEK-SYNTEZ. Shares Indie with MOLEK-SYNTEZ.
Eliza is a visual novel about an AI counseling program, the people who develop it, and the people who use it. Follow Evelyn Ishino-Aubrey as she reconnects with people from her past, gets to know the people of Seattle who use Eliza for counseling, and decides the course of her future.
Frequently asked about MOLEK-SYNTEZ
- Does MOLEK-SYNTEZ run on Steam Deck?
- MOLEK-SYNTEZ is rated Playable on Steam Deck — it runs, but expect some manual adjustments (control remapping, text size, or graphics settings) for the best experience.
- How much does MOLEK-SYNTEZ cost?
- MOLEK-SYNTEZ is listed on Steam at 9.99 USD (current store price; Steam sales may reduce this temporarily).
- What games are most similar to MOLEK-SYNTEZ?
- Based on Steam play patterns and shared genres/tags, the games most often recommended alongside MOLEK-SYNTEZ are Opus Magnum, SpaceChem, SHENZHEN I/O.
- Who developed MOLEK-SYNTEZ?
- MOLEK-SYNTEZ was developed by Zachtronics.
imho.run ranks Steam game alternatives using a mix of collaborative filtering (ALS / iALS / EASE / LightGCN), content scoring over genres, categories, Steam tags, developers, and publishers, plus AI-extracted vibes mined from review text. The page above is generated in seed mode anchored on MOLEK-SYNTEZ.
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