IMHO.

Games like MOLEK-SYNTEZ

If MOLEK-SYNTEZ is your kind of game, the closest matches are Opus Magnum, SpaceChem and SHENZHEN I/O — picked from the ranked list below. Reviewers single out its atmospheric, bleak and contemplative. Each pick is ranked by what players of this game also play, shared genres and tags, and review-mined similarity — not a generic popularity list.

Get personalized picks →

About MOLEK-SYNTEZ: Use the MOLEK-SYNTEZ to create small molecules with various pharmacological effects from the comfort of your small Romanian apartment.

2019IndieSimulation9.99 USDDeck PlayableWindows · macOS · Linuxby Zachtronics
MOLEK-SYNTEZ — Steam game cover
Players highlight
Cold dystopian narrative enhances immersionDiscover mechanics through experimentation with no tutorialProgramming emitters to rearrange molecules feels uniquely satisfyingAtmosphericBleakContemplative

Players who liked MOLEK-SYNTEZ also play

Steam players who put hours into MOLEK-SYNTEZ also tend to own these titles — a signal called collaborative filtering. imho.run cross-references millions of library ownership patterns to surface games whose real audiences overlap, regardless of whether their genre tags match.

  1. Opus Magnum

    WHY THIS

    Shares a contemplative mood with MOLEK-SYNTEZ.

    Top pick for MOLEK-SYNTEZ fans by collaborative filtering across millions of Steam libraries. Shares Indie and Simulation with MOLEK-SYNTEZ.

    Opus Magnum is the latest open-ended puzzle game from Zachtronics, the creators of SpaceChem, Infinifactory, and SHENZHEN I/O. Design and build machines that assemble potions, poisons, and more using the alchemical engineer’s most advanced tool: the transmutation engine!

    2017IndieSimulation19.99 USDDeck PlayableSteam ↗
  2. SpaceChem

    WHY THIS

    Shares a contemplative mood with MOLEK-SYNTEZ.

    Second-strongest match for MOLEK-SYNTEZ fans by collaborative filtering across millions of Steam libraries. Shares Indie and Simulation with MOLEK-SYNTEZ.

    Zachtronics is back with an ambitious new design-based puzzle game. Take on the role of a Reactor Engineer working for SpaceChem, the leading chemical synthesizer for frontier colonies. Construct elaborate factories to transform raw materials into valuable chemical products!

    2011IndieSimulation9.99 USDDeck PlayableSteam ↗
  3. SHENZHEN I/O

    WHY THIS

    Shares a contemplative mood with MOLEK-SYNTEZ.

    Third-strongest match for MOLEK-SYNTEZ fans by collaborative filtering across millions of Steam libraries. Shares Indie and Simulation with MOLEK-SYNTEZ.

    BUILD CIRCUITS. WRITE CODE. RTFM.

    2016IndieSimulation14.99 USDDeck PlayableSteam ↗
  4. EXAPUNKS

    WHY THIS

    Shares an atmospheric mood with MOLEK-SYNTEZ.

    Ranked #4 for MOLEK-SYNTEZ fans by collaborative filtering across millions of Steam libraries. Shares Indie and Simulation with MOLEK-SYNTEZ.

    The year is 1997. You used to be a hacker, but now you have the phage. You made a deal: one hack, one dose. There’s nothing left to lose… except your life.

    2018IndieSimulation19.99 USDDeck PlayableSteam ↗
  5. TIS-100

    WHY THIS

    Ranked #5 for MOLEK-SYNTEZ fans by collaborative filtering across millions of Steam libraries. Shares Indie and Simulation with MOLEK-SYNTEZ.

    TIS-100 is an open-ended programming game by Zachtronics, the creators of SpaceChem and Infinifactory, in which you rewrite corrupted code segments to repair the TIS-100 and unlock its secrets. It’s the assembly language programming game you never asked for!

    2015IndieSimulation6.99 USDSteam ↗
  6. Comet 64

    WHY THIS

    Shares an atmospheric mood with MOLEK-SYNTEZ.

    Ranked #6 for MOLEK-SYNTEZ fans by collaborative filtering across millions of Steam libraries. Shares Indie and Simulation with MOLEK-SYNTEZ.

    Comet 64 is a programming puzzle game. The year is 1984. All you got is a Comet 64 home computer and the operator's manual it came with.

    2021IndieSimulation14.99 USDDeck PlayableSteam ↗
  7. Kaizen: A Factory Story

    WHY THIS

    Shares an atmospheric mood with MOLEK-SYNTEZ.

    Ranked #7 for MOLEK-SYNTEZ fans by collaborative filtering across millions of Steam libraries. Shares Simulation with MOLEK-SYNTEZ.

    Kaizen is an open-ended puzzle automation game from the original Zachtronics team, set in 1980s Japan. Design, build, and optimize production lines to create iconic products, like calculators, camcorders, and arcade machines.

    2025StrategySimulation9.99 USDDeck PlayableSteam ↗
  8. Infinifactory

    WHY THIS

    Ranked #8 for MOLEK-SYNTEZ fans by collaborative filtering across millions of Steam libraries. Shares Indie and Simulation with MOLEK-SYNTEZ.

    Infinifactory is a sandbox puzzle game by Zachtronics, the creators of SpaceChem and Infiniminer. Build factories that assemble products for your alien overlords, and try not to die in the process.

    2015IndieSimulation24.99 USDDeck PlayableSteam ↗

Reviewers mention these as similar to MOLEK-SYNTEZ

Surfaced from review text: when other players write 'if you liked X, try Y', we catch the name and resolve it back to a Steam game.

  1. TIS-100

    WHY THIS

    Reviewers of MOLEK-SYNTEZ cross-mention this title as a similar play. Shares Indie and Simulation with MOLEK-SYNTEZ.

    TIS-100 is an open-ended programming game by Zachtronics, the creators of SpaceChem and Infinifactory, in which you rewrite corrupted code segments to repair the TIS-100 and unlock its secrets. It’s the assembly language programming game you never asked for!

    2015IndieSimulation6.99 USDSteam ↗
  2. SHENZHEN I/O

    WHY THIS

    Shares a contemplative mood with MOLEK-SYNTEZ.

    Reviewers of MOLEK-SYNTEZ cross-mention this title as a similar play. Shares Indie and Simulation with MOLEK-SYNTEZ.

    BUILD CIRCUITS. WRITE CODE. RTFM.

    2016IndieSimulation14.99 USDDeck PlayableSteam ↗
  3. Opus Magnum

    WHY THIS

    Shares a contemplative mood with MOLEK-SYNTEZ.

    Reviewers of MOLEK-SYNTEZ cross-mention this title as a similar play. Shares Indie and Simulation with MOLEK-SYNTEZ.

    Opus Magnum is the latest open-ended puzzle game from Zachtronics, the creators of SpaceChem, Infinifactory, and SHENZHEN I/O. Design and build machines that assemble potions, poisons, and more using the alchemical engineer’s most advanced tool: the transmutation engine!

    2017IndieSimulation19.99 USDDeck PlayableSteam ↗
  4. SpaceChem

    WHY THIS

    Shares a contemplative mood with MOLEK-SYNTEZ.

    Reviewers of MOLEK-SYNTEZ cross-mention this title as a similar play. Shares Indie and Simulation with MOLEK-SYNTEZ.

    Zachtronics is back with an ambitious new design-based puzzle game. Take on the role of a Reactor Engineer working for SpaceChem, the leading chemical synthesizer for frontier colonies. Construct elaborate factories to transform raw materials into valuable chemical products!

    2011IndieSimulation9.99 USDDeck PlayableSteam ↗
  5. EXAPUNKS

    WHY THIS

    Shares an atmospheric mood with MOLEK-SYNTEZ.

    Reviewers of MOLEK-SYNTEZ cross-mention this title as a similar play. Shares Indie and Simulation with MOLEK-SYNTEZ.

    The year is 1997. You used to be a hacker, but now you have the phage. You made a deal: one hack, one dose. There’s nothing left to lose… except your life.

    2018IndieSimulation19.99 USDDeck PlayableSteam ↗

Cheaper alternatives

Games in the same vein priced at least 40% below MOLEK-SYNTEZ at current Steam store prices.

  1. Garry's Mod

    WHY THIS

    Priced ~50% under MOLEK-SYNTEZ on Steam right now. Shares Indie and Simulation with MOLEK-SYNTEZ.

    Garry's Mod is a physics sandbox. There aren't any predefined aims or goals. We give you the tools and leave you to play.

    2006IndieSimulationCasual4.99 USDDeck PlayableSteam ↗
  2. Vampire Survivors

    WHY THIS

    Priced ~50% under MOLEK-SYNTEZ on Steam right now. Shares Indie with MOLEK-SYNTEZ.

    Mow down thousands of night creatures and survive until dawn! Vampire Survivors is a gothic horror casual game with rogue-lite elements, where your choices can allow you to quickly snowball against the hundreds of monsters that get thrown at you. Be the bullet hell!

    2022ActionIndieRPG4.99 USDDeck VerifiedSteam ↗
  3. Cookie Clicker

    WHY THIS

    Priced ~50% under MOLEK-SYNTEZ on Steam right now. Shares Indie and Simulation with MOLEK-SYNTEZ.

    An idle game about making cookies! Originally released in 2013 on the web, and actively developed since then. This is the official version for Steam.

    2021StrategyIndieSimulation4.99 USDDeck PlayableSteam ↗
  4. WEBFISHING

    WHY THIS

    Priced ~50% under MOLEK-SYNTEZ on Steam right now. Shares Indie with MOLEK-SYNTEZ.

    WEBFISHING a multiplayer chatroom-focused fishing game! Relax and fish (on the web!)

    2024IndieMassively MultiplayerCasual4.99 USDSteam ↗
  5. POSTAL 2

    WHY THIS

    Priced ~90% under MOLEK-SYNTEZ on Steam right now. Shares Indie with MOLEK-SYNTEZ.

    Live a week in the life of "The POSTAL Dude"; a hapless everyman just trying to check off some chores. Buying milk, returning an overdue library book, getting Gary Coleman's autograph, what could possibly go wrong?

    2012ActionIndieAdventure0.99 USDDeck VerifiedSteam ↗
  6. Buckshot Roulette

    WHY THIS

    Priced ~70% under MOLEK-SYNTEZ on Steam right now. Shares Indie and Simulation with MOLEK-SYNTEZ.

    Play Russian roulette with a 12-gauge shotgun. Four enter. One leaves. Roll the dice with your life. Good luck!

    2024ActionIndieSimulation2.99 USDDeck PlayableSteam ↗
  7. Brotato

    WHY THIS

    Priced ~50% under MOLEK-SYNTEZ on Steam right now. Shares Indie with MOLEK-SYNTEZ.

    Brotato is a top-down arena shooter roguelite where you play a potato wielding up to 6 weapons at a time to fight off hordes of aliens. Choose from a variety of traits and items to create unique builds and survive until help arrives.

    2023ActionIndieRPG4.99 USDDeck VerifiedSteam ↗
  8. Your Only Move Is HUSTLE

    WHY THIS

    Priced ~50% under MOLEK-SYNTEZ on Steam right now. Shares Indie and Simulation with MOLEK-SYNTEZ.

    Master your technique, execute flashy combos, and outsmart opponents across the world, frame-by-frame. Slow down the clock to fine-tune your fighting style in this innovative, turn-based combat simulator. Pulverize your friends and choreograph spectacular fight scenes. No training mode required.

    2023ActionStrategyIndie4.99 USDDeck PlayableSteam ↗

Free alternatives

Free-to-play games that recommended players of this title also tend to enjoy.

  1. Steam Engine Simulator

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Simulation with MOLEK-SYNTEZ.

    The Steam Engine Simulator shown on AngeTheGreat's YouTube channel.

    2023SimulationFreeDeck VerifiedSteam ↗
  2. last seen online

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie and Simulation with MOLEK-SYNTEZ.

    Look through someone else’s computer. Inspired by early “escape room” flash games.

    2024IndieSimulationFree To PlayFreeDeck PlayableSteam ↗
  3. Mizi NO!

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with MOLEK-SYNTEZ.

    In this free 2D puzzle game, you must reassemble broken objects that your cat has knocked over.

    2024IndieCasualFreeDeck PlayableSteam ↗
  4. Jigsaw Puzzle Dreams

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with MOLEK-SYNTEZ.

    Beautiful Multiplayer Jigsaw Puzzle game where you can design the room you play in!

    2021IndieFree To PlayCasualFreeDeck PlayableSteam ↗
  5. Learn to Fly 3

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with MOLEK-SYNTEZ.

    Build your spaceship from scratch, earn funds and invest them into building a bigger, better spaceship as you try and fly your way up to space!

    2017ActionStrategyIndieFreeDeck PlayableSteam ↗
  6. World of Guns: Gun Disassembly

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie and Simulation with MOLEK-SYNTEZ.

    World of Guns: Gun Disassembly lets you delve into the inner workings of guns from the largest gears to the smallest screws

    2014ActionStrategyIndieFreeDeck VerifiedSteam ↗
  7. Revolution Idle

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie and Simulation with MOLEK-SYNTEZ.

    Join an experience where each revolution takes you further into the unknown! Revolution Idle challenges you to multiply your accumulators to reach unimaginable heights. Will you manage to reach infinity?

    2025IndieSimulationFree To PlayFreeDeck PlayableSteam ↗
  8. Viridi

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie and Simulation with MOLEK-SYNTEZ.

    Nurture a small pot of succulents that grow in real time. Viridi is a safe haven, a place you can return to for a moment of peace and quiet whenever you need it.

    2015IndieSimulationFree To PlayFreeDeck PlayableSteam ↗

More from Zachtronics

Other recommendable Steam games by Zachtronics, ranked by review count so the studio's hits land first.

  1. Opus Magnum

    WHY THIS

    Shares a contemplative mood with MOLEK-SYNTEZ.

    Another title from Zachtronics, the studio behind MOLEK-SYNTEZ. Shares Indie and Simulation with MOLEK-SYNTEZ.

    Opus Magnum is the latest open-ended puzzle game from Zachtronics, the creators of SpaceChem, Infinifactory, and SHENZHEN I/O. Design and build machines that assemble potions, poisons, and more using the alchemical engineer’s most advanced tool: the transmutation engine!

    2017IndieSimulation19.99 USDDeck PlayableSteam ↗
  2. SHENZHEN I/O

    WHY THIS

    Shares a contemplative mood with MOLEK-SYNTEZ.

    Another title from Zachtronics, the studio behind MOLEK-SYNTEZ. Shares Indie and Simulation with MOLEK-SYNTEZ.

    BUILD CIRCUITS. WRITE CODE. RTFM.

    2016IndieSimulation14.99 USDDeck PlayableSteam ↗
  3. TIS-100

    WHY THIS

    Another title from Zachtronics, the studio behind MOLEK-SYNTEZ. Shares Indie and Simulation with MOLEK-SYNTEZ.

    TIS-100 is an open-ended programming game by Zachtronics, the creators of SpaceChem and Infinifactory, in which you rewrite corrupted code segments to repair the TIS-100 and unlock its secrets. It’s the assembly language programming game you never asked for!

    2015IndieSimulation6.99 USDSteam ↗
  4. SpaceChem

    WHY THIS

    Shares a contemplative mood with MOLEK-SYNTEZ.

    Another title from Zachtronics, the studio behind MOLEK-SYNTEZ. Shares Indie and Simulation with MOLEK-SYNTEZ.

    Zachtronics is back with an ambitious new design-based puzzle game. Take on the role of a Reactor Engineer working for SpaceChem, the leading chemical synthesizer for frontier colonies. Construct elaborate factories to transform raw materials into valuable chemical products!

    2011IndieSimulation9.99 USDDeck PlayableSteam ↗
  5. Infinifactory

    WHY THIS

    Another title from Zachtronics, the studio behind MOLEK-SYNTEZ. Shares Indie and Simulation with MOLEK-SYNTEZ.

    Infinifactory is a sandbox puzzle game by Zachtronics, the creators of SpaceChem and Infiniminer. Build factories that assemble products for your alien overlords, and try not to die in the process.

    2015IndieSimulation24.99 USDDeck PlayableSteam ↗
  6. EXAPUNKS

    WHY THIS

    Shares an atmospheric mood with MOLEK-SYNTEZ.

    Another title from Zachtronics, the studio behind MOLEK-SYNTEZ. Shares Indie and Simulation with MOLEK-SYNTEZ.

    The year is 1997. You used to be a hacker, but now you have the phage. You made a deal: one hack, one dose. There’s nothing left to lose… except your life.

    2018IndieSimulation19.99 USDDeck PlayableSteam ↗
  7. Last Call BBS

    WHY THIS

    Shares an atmospheric mood with MOLEK-SYNTEZ.

    Another title from Zachtronics, the studio behind MOLEK-SYNTEZ. Shares Indie and Simulation with MOLEK-SYNTEZ.

    Boot up your Z5 Powerlance and dial into Last Call BBS, the last game from Zachtronics! The Barkeep’s loaded up his retro computer with a full set of puzzle games for you to download and play. No need to worry about copy protection, they’re all fully cracked and ready to enjoy!

    2022IndieSimulation19.99 USDDeck PlayableSteam ↗
  8. Eliza

    WHY THIS

    Shares an atmospheric mood with MOLEK-SYNTEZ.

    Another title from Zachtronics, the studio behind MOLEK-SYNTEZ. Shares Indie with MOLEK-SYNTEZ.

    Eliza is a visual novel about an AI counseling program, the people who develop it, and the people who use it. Follow Evelyn Ishino-Aubrey as she reconnects with people from her past, gets to know the people of Seattle who use Eliza for counseling, and decides the course of her future.

    2019Indie7.49 USDDeck PlayableSteam ↗

Frequently asked about MOLEK-SYNTEZ

Does MOLEK-SYNTEZ run on Steam Deck?
MOLEK-SYNTEZ is rated Playable on Steam Deck — it runs, but expect some manual adjustments (control remapping, text size, or graphics settings) for the best experience.
How much does MOLEK-SYNTEZ cost?
MOLEK-SYNTEZ is listed on Steam at 9.99 USD (current store price; Steam sales may reduce this temporarily).
What games are most similar to MOLEK-SYNTEZ?
Based on Steam play patterns and shared genres/tags, the games most often recommended alongside MOLEK-SYNTEZ are Opus Magnum, SpaceChem, SHENZHEN I/O.
Who developed MOLEK-SYNTEZ?
MOLEK-SYNTEZ was developed by Zachtronics.

imho.run ranks Steam game alternatives using a mix of collaborative filtering (ALS / iALS / EASE / LightGCN), content scoring over genres, categories, Steam tags, developers, and publishers, plus AI-extracted vibes mined from review text. The page above is generated in seed mode anchored on MOLEK-SYNTEZ.

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