Single-player games like Metavaxx
Below are 17 single-player Steam games similar to Metavaxx, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Metavaxx page.
Ranked picks
- 1

Genome Guardian
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Action with Metavaxx.
COMBINE WEAPONS in the microscopic roguelite turret shooter with macroscopic depth. Survive 6 modes using an astounding array of turrets, perks, mutations and power-ups on this psychedelic journey to the heart of the abyss. Shmup Mode turns it into a vertical shoot 'em up!
- 2

Hive Jump 2: Survivors
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Action with Metavaxx.
Become an agent of vengeance in this bullet-heaven action roguelite! You are the lone survivor of your squad, on an alien planet with just your weapon, a jetpack, and the courage to keep fighting. Kill off alien swarms and transform their valuable guts into explosive upgrades and vital utilities.
- 3

Survivors of the Dawn
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Action with Metavaxx.
A roguelite horde-survival bullet heaven with QUINTILLIONS of bullets over QUINTILLIONS of hordes. Mix weapons with items, modify, control chaos at terminals and break through tightening waves.
- 4

Tesla vs Lovecraft
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Action with Metavaxx.
Tesla vs Lovecraft is an intense top-down twin stick arena shooter from the creators of Crimsonland and Neon Chrome. Play as the enigmatic inventor Nikola Tesla harnessing the static energy to power up Tesla-Mech and give the lovecraftian nightmares a lesson in horror!
- 5

Utopia Must Fall
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Action with Metavaxx.
Defend humanity's last surviving metropolis from mysterious alien machinations in this challenging base-defense arcade shooter. Featuring rapid upgrade progression, procedurally generated attack waves, dark humor and laser-sharp aesthetics.
- 6

CRYPTARK
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Action and Strategy with Metavaxx.
Cryptark is a 2D sci-fi shooter where you take on the role of a heavily armed privateer seeking to earn government contracts by boarding deadly alien space-hulks. It's up to you to strategize a plan of attack, pick an equipment loadout, and destroy the central core to be victorious.
- 7

Beyond the Long Night
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Action with Metavaxx.
Explore a whimsical underground world whilst being chased by a mysterious corrupting force in this charming twin-stick action roguelike! Befriend loveable characters, fend off enemies with chaotic abilities, and uncover the secrets of this subterranean kingdom caught in a time loop.
- 8

Teleglitch: Die More Edition
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Action with Metavaxx.
In a cold, dark future dominated by mega-corporations, a small lonely planet on the edge of habitable space is the site of a shadowy research facility specializing in necrotic tissue reactivation. You are a scientist who has suddenly awoken to the realization that you are the lone survivor.
- 9

DemonCrawl
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Strategy with Metavaxx.
DemonCrawl is a puzzle roguelite that combines the addicting gameplay of Minesweeper with hundreds of unique items, stages, and abilities!
- 10

Shotgun King: The Final Checkmate
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Action and Strategy with Metavaxx.
Chess, but you replace your entire army with a royal shotgun. A unique strategy roguelike based on the timeless checkboard classic.
- 11

The Wratch's Den
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Strategy with Metavaxx.
A byte-sized Dungeon Keeping roguelike: dig out your lair, populate it with monsters and protect the Wratch from heroes come for easy prestige.
- 12

MOONPONG: Tales of Epic Lunacy
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Action with Metavaxx.
Psychedelic Roguelite Pong 'em up where you go to bring back the Moon. A crazy, addictive, and hilarious arcade-action game based on the granddad of all video games.
- 13

Spectrum Forces
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Action with Metavaxx.
Make up your squads out of 9 unique spaceships and go clear 3 planets from hordes of robots in not-so-classic horizontal shoot-em-up style!
- 14

Scavenger of Dunomini
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Action and Strategy with Metavaxx.
The world's first match-3 trash pile defender! Protect and manage your pile of garbage while recycling it into deadly defenses against thieving drones.
- 15

Rush for the Ages
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Strategy with Metavaxx.
Remake history and race your opponents for a complete and glorious timeline in this lightning-fast card game.
- 16

Ecstatic
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Action with Metavaxx.
Rave spider goes to the bullet-hell ball: shoot rockets out of your butt, dodge and destroy waves upon waves of drones, slow down time whenever you don't move.
- 17

Pigments
Single-player alternative to Metavaxx — playable solo, no multiplayer required. Shares Action with Metavaxx.
Be a fruit locked in a room, dodge circular saws and paint as much of the level as you can.