Games like Genome Guardian
If Genome Guardian is your kind of game, the closest matches are Genome Guardian 2, Hive Jump 2: Survivors and NIMRODS — picked from the ranked list below. Reviewers single out its atmospheric, challenging and hypnotic. Each pick is ranked by what players of this game also play, shared genres and tags, and review-mined similarity — not a generic popularity list.
Get personalized picks →About Genome Guardian: COMBINE WEAPONS in the microscopic roguelite turret shooter with macroscopic depth. Survive 6 modes using an astounding array of turrets, perks, mutations and power-ups on this psychedelic journey to the heart of the abyss. Shmup Mode turns it into a vertical shoot 'em up!
Players who liked Genome Guardian also play
Steam players who put hours into Genome Guardian also tend to own these titles — a signal called collaborative filtering. imho.run cross-references millions of library ownership patterns to surface games whose real audiences overlap, regardless of whether their genre tags match.
Genome Guardian 2
WHY THIS
Shares wave based survival, loadout customization, roguelite and an atmospheric mood with Genome Guardian.
Top pick for Genome Guardian fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with Genome Guardian.
COMBINE WEAPONS in the microscopic shooter with macroscopic depth. BUILD YOUR NANOBOT from hundreds of parts. SURVIVE the microbial onslaught once more in this psychedelic dive to the Abyss, full of mutations, minerals, anomalies and powerup polyps. SHMUP mode turns it into a vertical shoot 'em up!
Hive Jump 2: Survivors
WHY THIS
Shares combo based combat, build variety, action shooter and a stressful mood with Genome Guardian.
Second-strongest match for Genome Guardian fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with Genome Guardian.
Become an agent of vengeance in this bullet-heaven action roguelite! You are the lone survivor of your squad, on an alien planet with just your weapon, a jetpack, and the courage to keep fighting. Kill off alien swarms and transform their valuable guts into explosive upgrades and vital utilities.
NIMRODS
WHY THIS
Shares meta progression, procedural generation and a stressful mood with Genome Guardian.
Third-strongest match for Genome Guardian fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with Genome Guardian.
Assemble a limitless arsenal in this survive-em-up roguelite shooter. As a Gun Manufacturer's testing force, your mission is simple: test the latest gun tech and scavenge alien planets. Collect insane weapon parts to invent crazy guns that slay thousands. You may not survive, but your guns will!
Nuclear Throne
WHY THIS
Shares a stressful mood with Genome Guardian.
Ranked #4 for Genome Guardian fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with Genome Guardian.
Nuclear Throne is a post-apocalyptic roguelike-like top-down shooter. Not 'the final hope of humanity' post-apocalyptic, but 'humanity is extinct and mutants and monsters now roam the world' post-apocalyptic. Can you reach the Nuclear Throne?
Defend Earth: Xenos Survivors
WHY THIS
Shares an atmospheric mood with Genome Guardian.
Ranked #5 for Genome Guardian fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with Genome Guardian.
You are Earth's last line of defense in a relentless alien invasion. Experience intense top-down roguelite action across diverse landscapes, fighting invaders with a versatile arsenal. Outsmart, outgun, and survive your foes. Every run increases the challenge - so adapt, evolve, dominate!
Brotato
WHY THIS
Shares procedural generation and a challenging mood with Genome Guardian.
Ranked #6 for Genome Guardian fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with Genome Guardian.
Brotato is a top-down arena shooter roguelite where you play a potato wielding up to 6 weapons at a time to fight off hordes of aliens. Choose from a variety of traits and items to create unique builds and survive until help arrives.
Rocket Rats
WHY THIS
Shares wave based survival, combo based combat, indie and an atmospheric mood with Genome Guardian.
Ranked #7 for Genome Guardian fans by collaborative filtering across millions of Steam libraries. Shares Action and Casual with Genome Guardian.
Rocket Rats is a survivors-like game where you defeat cheese-based astral bodies in space – as a rat! Clear waves of enemies, collect cheese, upgrade your gear, and conquer the moon!
Atomicrops
WHY THIS
Ranked #8 for Genome Guardian fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with Genome Guardian.
A twin-stick, bullet-hell, roguelite where you must cultivate and defend the last farm in a post-apocalyptic wasteland. Farm mutated crops, upgrade your weapons, marry townsfolk, and kill every mutant creature that tries to invade your homestead! Yee-haw!
Cheaper alternatives
Games in the same vein priced at least 40% below Genome Guardian at current Steam store prices.
Garry's Mod
WHY THIS
Priced ~58% under Genome Guardian on Steam right now. Shares Indie and Casual with Genome Guardian.
Garry's Mod is a physics sandbox. There aren't any predefined aims or goals. We give you the tools and leave you to play.
Vampire Survivors
WHY THIS
Priced ~58% under Genome Guardian on Steam right now. Shares Action and Indie with Genome Guardian.
Mow down thousands of night creatures and survive until dawn! Vampire Survivors is a gothic horror casual game with rogue-lite elements, where your choices can allow you to quickly snowball against the hundreds of monsters that get thrown at you. Be the bullet hell!
R.E.P.O.
WHY THIS
Priced ~42% under Genome Guardian on Steam right now. Shares Action with Genome Guardian.
An online co-op horror game with up to 6 players. Locate valuable, fully physics-based objects and handle them with care as you retrieve and extract to satisfy your creator's desires.
Titanfall® 2
WHY THIS
Priced ~63% under Genome Guardian on Steam right now. Shares Action with Genome Guardian.
Respawn Entertainment gives you the most advanced titan technology in its new, single player campaign & multiplayer experience. Combine & conquer with new titans & pilots, deadlier weapons, & customization and progression systems that help you and your titan flow as one unstoppable killing force.
Slay the Spire
WHY THIS
Priced ~48% under Genome Guardian on Steam right now. Shares Indie with Genome Guardian.
We fused card games and roguelikes together to make the best single player deckbuilder we could. Craft a unique deck, encounter bizarre creatures, discover relics of immense power, and Slay the Spire!
Cookie Clicker
WHY THIS
Priced ~58% under Genome Guardian on Steam right now. Shares Indie and Casual with Genome Guardian.
An idle game about making cookies! Originally released in 2013 on the web, and actively developed since then. This is the official version for Steam.
WEBFISHING
WHY THIS
Priced ~58% under Genome Guardian on Steam right now. Shares Indie and Casual with Genome Guardian.
WEBFISHING a multiplayer chatroom-focused fishing game! Relax and fish (on the web!)
POSTAL 2
WHY THIS
Priced ~92% under Genome Guardian on Steam right now. Shares Action and Indie with Genome Guardian.
Live a week in the life of "The POSTAL Dude"; a hapless everyman just trying to check off some chores. Buying milk, returning an overdue library book, getting Gary Coleman's autograph, what could possibly go wrong?
Free alternatives
Free-to-play games that recommended players of this title also tend to enjoy.
Life is Strange - Episode 1
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Action with Genome Guardian.
Episode 1 now FREE! Life is Strange is an award-winning and critically acclaimed episodic adventure game that allows the player to rewind time and affect the past, present and future.
Ultimate Custom Night
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Action and Indie with Genome Guardian.
Welcome to the ultimate FNAF mashup, featuring 50 selectable characters and custom difficulties!
Bongo Cat
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with Genome Guardian.
Bongo cat needs your help. Bongo cat needz more hatz!!! Every time you press a key, Bongo cat will punch your taskbar. Type, click, play, work to collect more points. Which hats will you find?
Indigo Park: Chapter 1
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Action and Indie with Genome Guardian.
Explore the abandoned childhood wonder of Indigo Park! Guided by Rambley the Raccoon, help restore power to the destroyed amusement park while you run from the reason it shut down.
STRAFTAT
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Action with Genome Guardian.
STRAFTAT is a 1v1/2v2 ONLINE first person SHOOTER with quick rounds in over 350 MAPS ; Including all WEAPONS, proximity chat and 4 players FFA.
Grimm's Hollow
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie and RPG with Genome Guardian.
A spooky, freeware RPG where you search the afterlife for your brother. Reap ghosts with your scythe, explore haunted caves, and eat ghostly treats on your journey through death.
Virtual Cottage
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie and Casual with Genome Guardian.
Virtual Cottage gives you a comfy place to rest and be productive without any distractions. Open the game, set yourself a goal and enjoy the atmosphere.
Narrow it down
Head-to-head comparisons
Plays great on Steam Deck
Valve-Verified or Playable picks from the similar pool — ready to go on Deck out of the box.
Hive Jump 2: Survivors
WHY THIS
Shares combo based combat, build variety, action shooter and a stressful mood with Genome Guardian.
Deck Verified — runs on Steam Deck out of the box. Shares Action and Indie with Genome Guardian.
Become an agent of vengeance in this bullet-heaven action roguelite! You are the lone survivor of your squad, on an alien planet with just your weapon, a jetpack, and the courage to keep fighting. Kill off alien swarms and transform their valuable guts into explosive upgrades and vital utilities.
NIMRODS
WHY THIS
Shares meta progression, procedural generation and a stressful mood with Genome Guardian.
Deck Verified — runs on Steam Deck out of the box. Shares Action and Indie with Genome Guardian.
Assemble a limitless arsenal in this survive-em-up roguelite shooter. As a Gun Manufacturer's testing force, your mission is simple: test the latest gun tech and scavenge alien planets. Collect insane weapon parts to invent crazy guns that slay thousands. You may not survive, but your guns will!
Nuclear Throne
WHY THIS
Shares a stressful mood with Genome Guardian.
Deck Verified — runs on Steam Deck out of the box. Shares Action and Indie with Genome Guardian.
Nuclear Throne is a post-apocalyptic roguelike-like top-down shooter. Not 'the final hope of humanity' post-apocalyptic, but 'humanity is extinct and mutants and monsters now roam the world' post-apocalyptic. Can you reach the Nuclear Throne?
Brotato
WHY THIS
Shares procedural generation and a challenging mood with Genome Guardian.
Deck Verified — runs on Steam Deck out of the box. Shares Action and Indie with Genome Guardian.
Brotato is a top-down arena shooter roguelite where you play a potato wielding up to 6 weapons at a time to fight off hordes of aliens. Choose from a variety of traits and items to create unique builds and survive until help arrives.
Rocket Rats
WHY THIS
Shares wave based survival, combo based combat, indie and an atmospheric mood with Genome Guardian.
Deck Verified — runs on Steam Deck out of the box. Shares Action and Casual with Genome Guardian.
Rocket Rats is a survivors-like game where you defeat cheese-based astral bodies in space – as a rat! Clear waves of enemies, collect cheese, upgrade your gear, and conquer the moon!
Frequently asked about Genome Guardian
- Does Genome Guardian run on Steam Deck?
- Genome Guardian is rated Playable on Steam Deck — it runs, but expect some manual adjustments (control remapping, text size, or graphics settings) for the best experience.
- How much does Genome Guardian cost?
- Genome Guardian is listed on Steam at 11.99 USD (current store price; Steam sales may reduce this temporarily).
- What games are most similar to Genome Guardian?
- Based on Steam play patterns and shared genres/tags, the games most often recommended alongside Genome Guardian are Genome Guardian 2, Hive Jump 2: Survivors, NIMRODS.
- Who developed Genome Guardian?
- Genome Guardian was developed by Alpherior.
imho.run ranks Steam game alternatives using a mix of collaborative filtering (ALS / iALS / EASE / LightGCN), content scoring over genres, categories, Steam tags, developers, and publishers, plus AI-extracted vibes mined from review text. The page above is generated in seed mode anchored on Genome Guardian.
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