Single-player games like Systematic Immunity
Below are 8 single-player Steam games similar to Systematic Immunity, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Systematic Immunity page.
Ranked picks
- 1
Plazma Being
Single-player alternative to Systematic Immunity — playable solo, no multiplayer required. Shares Action and Indie with Systematic Immunity.
Take control of Zeb in this puzzle/platformer. He is a small energy based life form from space, known as a Plazma Being. While journeying through space to his home, Zeb was surprised to find that he was being kidnapped by aliens. They took him back to their planet and unceremoniously threw him into captivity.
- 2
Dead Cells
Single-player alternative to Systematic Immunity — playable solo, no multiplayer required. Shares Action and Indie with Systematic Immunity.
Dead Cells is a roguelite, metroidvania inspired, action-platformer. You'll explore a sprawling, ever-changing castle... assuming you’re able to fight your way past its keepers in 2D souls-lite combat. No checkpoints. Kill, die, learn, repeat.
- 3
The End Is Nigh
Single-player alternative to Systematic Immunity — playable solo, no multiplayer required. Shares Action and Indie with Systematic Immunity.
The End Is Nigh is a sprawling adventure platformer where you die a lot, but thats ok because you are probably already dead anyway.
- 4
INK
Single-player alternative to Systematic Immunity — playable solo, no multiplayer required. Shares Action and Indie with Systematic Immunity.
INK is a fast-paced platformer about using colorful paint to uncover your surroundings. Defeat all enemies in the room and reach the goal! However, the terrain is invisible, so you need to discover the terrain by physically bumping into it, by performing a double jump or by, well, dying.
- 5
Jelly Killer
Single-player alternative to Systematic Immunity — playable solo, no multiplayer required. Shares Action and Indie with Systematic Immunity.
Jelly Killer - Retro Platformer The Adventures Of A Young Bioweapon. In this game you will act like the young bioweapon. You will encounter lots of traps and puzzles. You will have to possess human bodies to pass the game to the end. Good luck!
- 6
Neon White
Single-player alternative to Systematic Immunity — playable solo, no multiplayer required. Shares Action and Indie with Systematic Immunity.
Neon White is a single-player speedrunning FPS where you can sacrifice your guns for godlike parkour moves.
- 7
Dex
Single-player alternative to Systematic Immunity — playable solo, no multiplayer required. Shares Action and Indie with Systematic Immunity.
Dex is a 2D, side-scrolling, open-world cyberpunk RPG with a focus on exploration and non-linear gameplay.
- 8
Semblance
Single-player alternative to Systematic Immunity — playable solo, no multiplayer required. Shares Action and Indie with Systematic Immunity.
Semblance is an innovative platformer with deformable terrain, set in a beautiful minimalist world. It’s a game that asks, what if you could deform and reshape the world itself? Semblance takes the idea of a ‘platform’ in a platformer and turns it on its head.