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Games like Systematic Immunity

  • 19 games
  • Updated May 4, 2026

Players who liked Systematic Immunity also play

The closest matches to Systematic Immunity: Plazma Being, Dead Cells, The End Is Nigh, INK, and Jelly Killer. Ranked by imho.run from Steam co-play data, shared tags and reviews.

  1. Rank 04

    INK

    • $4.99 (Price checked Nov 7)
    • Deck Verified
    • 2015
  2. Rank 06

    Neon White

    • $24.99 (Price checked Nov 6)
    • Deck Verified
    • 2022
  3. Rank 07

    Dex

    • $19.99 (Price checked Nov 6)
    • 2015
  4. Rank 08

    Semblance

    • $9.99 (Price checked Nov 7)
    • Deck Verified
    • 2018

The full ranked list: top 24 games like Systematic Immunity

Best match first, as plain text. The same list for AI assistants:
  1. 1
    Plazma Being

    Genres: Action, Indie, Adventure

    • 65% of 75 reviews
  2. 2
    Dead Cells

    Genres: Action, Indie, Adventure

    • 96% of 43,598 reviews
  3. 3
    The End Is Nigh

    Genres: Action, Indie, Adventure

    • 93% of 1,896 reviews
  4. 4
    INK

    Genres: Action, Indie, Adventure

    • 86% of 470 reviews
  5. 5
    Jelly Killer

    Genres: Action, Indie, Adventure

    • 76% of 123 reviews
  6. 6
    Neon White

    Genres: Action, Indie, Adventure

    • 98% of 12,271 reviews
  7. 7
    Dex

    Genres: Action, Indie, Adventure

    • 84% of 1,492 reviews
  8. 8
    Semblance

    Genres: Action, Indie, Adventure

    • 85% of 160 reviews
  9. 9
    City Climber

    Genres: Action, Sports, Indie

    • 74% of 136 reviews
  10. 10
    ORCS

    Genres: Action, Indie, Adventure

    • 80% of 188 reviews
  11. 11
    Axiom Verge

    Genres: Action, Indie, Adventure

    • 90% of 4,057 reviews
  12. 12
    Skelattack

    Genres: Action, Indie, Adventure

    • 60% of 75 reviews
  13. 13
    Death's Gambit: Afterlife

    Genres: Action, Indie, Adventure

    • 80% of 2,088 reviews
  14. 14
    Flinthook

    Genres: Action, Indie, Adventure

    • 70% of 418 reviews
  15. 15
    Volgarr the Viking

    Genres: Action, Indie, Adventure

    • 83% of 1,036 reviews
  16. 16
    Freedom Planet

    Genres: Action, Indie

    • 96% of 2,488 reviews
  17. 17
    ScourgeBringer

    Genres: Action, Indie, Adventure

    • 89% of 1,214 reviews
  18. 18
    BUTCHER

    Genres: Action, Indie, Adventure

    • 90% of 621 reviews
  19. 19
    Aegis Defenders

    Genres: Action, Strategy, Indie

    • 76% of 96 reviews
  20. 20
    Angry Video Game Nerd Adventures

    Genres: Action, Indie, Adventure

    • 89% of 1,940 reviews
  21. 21
    Smelter

    Genres: Action, Strategy, Indie

    • 68% of 100 reviews
  22. 22
    Slime-san: Superslime Edition

    Genres: Action, Indie, Adventure

    • 86% of 59 reviews
  23. 23
    Iconoclasts

    Genres: Action, Indie, Adventure

    • 84% of 2,070 reviews
  24. 24
    Kotama and Academy Citadel

    Genres: Action, Indie, Adventure

    • 92% of 326 reviews
Systematic Immunity — Steam game cover
  • Released: 2016
  • Developer: Hedge Knight Games
  • Price: $3.99checked Nov 2
  • 60% of 5 reviews
  • Genres: Action, Indie, Adventure
  • Platforms: Windows

More games like Systematic Immunity, sliced differently

About Systematic Immunity

The closest matches to Systematic Immunity: Plazma Being, Dead Cells, The End Is Nigh, INK, and Jelly Killer. Ranked by imho.run from Steam co-play data, shared tags and reviews.

If Systematic Immunity is your kind of game, the closest matches are Plazma Being, Dead Cells and The End Is Nigh — picked from the ranked list below. Each pick is ranked by what players of this game also play, shared genres and tags, and review-mined similarity — not a generic popularity list.

About Systematic Immunity: Systematic Immunity is a challenging precision platformer set inside the human body...and not a particularly healthy one either. This body has been infected by a big, nasty bugger of a germ, who is making it his business to spawn many more germs as fast as he can.

Is Systematic Immunity worth buying?

Too few reviews to call

A summary of what players say, not a promise you'll like it. Every signal is listed below.

  • Only 5 Steam reviews so far, not enough to judge.
  • Price: $3.99 (checked Nov 2).

People who play it also play: Plazma Being, Dead Cells, The End Is Nigh

How this verdict works →

Frequently asked about Systematic Immunity

Can I run it?

How much does Systematic Immunity cost?

Systematic Immunity is listed on Steam at 3.99 USD (current store price; Steam sales may reduce this temporarily).

What games are most similar to Systematic Immunity?

Based on Steam play patterns and shared genres/tags, the games most often recommended alongside Systematic Immunity are Plazma Being, Dead Cells, The End Is Nigh.

Who developed Systematic Immunity?

Systematic Immunity was developed by Hedge Knight Games.