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Games like Chromosome Evil

  • 23 games
  • Updated May 4, 2026

Players who liked Chromosome Evil also play

The closest matches to Chromosome Evil: Chromosome Evil 2, Welcome Back, Commander, Flesh Eaters, Last Train Home, and They Are Billions. Ranked by imho.run from Steam co-play data, shared tags and reviews.

  1. Rank 01

    Why this

    Shares resource management with Chromosome Evil.

    • $1.99 (Price checked Nov 7)
    • Deck Playable
    • 2024
  2. Rank 02

    Why this

    Shares multiple endings and resource management with Chromosome Evil.

    • $7.79 (Price checked Nov 7)
    • Deck Playable
    • 2025
  3. Rank 03

    Why this

    Also Real Time Tactics and RTS, like Chromosome Evil.

    • $2.99 (Price checked Nov 7)
    • 2016
  1. Rank 05

    They Are Billions

    Why this: Also RTS and Zombies, like Chromosome Evil.

    • $29.99 (Price checked Nov 6)
    • Deck Playable
    • 2019
  2. Rank 06

    This War of Mine

    Why this: Also War and Post-apocalyptic, like Chromosome Evil.

    • $1.99 (Price checked Nov 7)
    • Deck Playable
    • 2014

The full ranked list: top 24 games like Chromosome Evil

Best match first, as plain text. The same list for AI assistants:
  1. 1
    Chromosome Evil 2

    Shares resource management with Chromosome Evil.

    • 88% of 105 reviews
  2. 2
    Welcome Back, Commander

    Shares multiple endings and resource management with Chromosome Evil.

    • 83% of 116 reviews
  3. 3
    Flesh Eaters

    Also Real Time Tactics and RTS, like Chromosome Evil.

    • 73% of 445 reviews
  4. 4
    Last Train Home

    Genres: Strategy

    • 88% of 2,194 reviews
  5. 5
    They Are Billions

    Also RTS and Zombies, like Chromosome Evil.

    • 80% of 18,746 reviews
  6. 6
    This War of Mine

    Also War and Post-apocalyptic, like Chromosome Evil.

    • 92% of 22,855 reviews
  7. 7
    Aliens: Dark Descent

    Genres: Action, Strategy

    • 88% of 9,060 reviews
  8. 8
    Atom Zombie Smasher

    Genres: Strategy, Indie

    • 90% of 927 reviews
  9. 9
    Dead State: Reanimated

    Also Zombies and Post-apocalyptic, like Chromosome Evil.

    • 71% of 1,503 reviews
  10. 10
    From Glory To Goo

    Also RTS and War, like Chromosome Evil.

    • 97% of 1,294 reviews
  11. 11
    March of the Living

    Genres: Strategy, Indie, Adventure

    • 70% of 347 reviews
  12. 12
    Cepheus Protocol

    Genres: Action, Strategy, Indie

    • 79% of 1,948 reviews
  13. 13
    Total War: ATTILA

    Genres: Strategy

    • 80% of 13,250 reviews
  14. 14
    Zombie Army Trilogy

    Genres: Action

    • 85% of 5,051 reviews
  15. 15
    Bad 2 Bad: Apocalypse

    Also Zombies and War, like Chromosome Evil.

    • 85% of 184 reviews
  16. 16
    Shadow Gambit: The Cursed Crew

    Genres: Strategy, RPG

    • 90% of 1,939 reviews
  17. 17
    Xenopurge

    Shares procedural mission generation and resource management with Chromosome Evil.

    • 89% of 201 reviews
  18. 18
    Strain Tactics

    Also Real Time Tactics and Zombies, like Chromosome Evil.

    • 87% of 157 reviews
  19. 19
    Faces of War

    Genres: Action, Strategy, Simulation

    • 81% of 207 reviews
  20. 20
    Men of War: Vietnam

    Shares squad based tactics with Chromosome Evil.

    • 57% of 529 reviews
  21. 21
    Beholder

    Genres: Strategy, Indie, Adventure

    • 82% of 3,028 reviews
  22. 22
    Broken Lines

    Shares multiple endings with Chromosome Evil.

    • 77% of 347 reviews
  23. 23
    Pathologic 3

    Also Psychological and Survival Horror, like Chromosome Evil.

    • 87% of 994 reviews
  24. 24
    Darwinia

    Genres: Strategy, Indie

    • 83% of 584 reviews
Chromosome Evil — Steam game cover
  • Released: 2022
  • Developer: S.C. 16 BIT NIGHTS S.R.L.
  • Price: $8.99−40%checked Nov 7
  • Steam Deck: Deck Playable
  • 82% of 221 reviews
  • Genres: Strategy
  • Platforms: Windows

Players highlight

  • Cosmic horror atmosphere immerses players
  • Limited resources force strategic choices
  • Multiple endings reward replayability
  • Atmospheric
  • Dark
  • Grim

More games like Chromosome Evil, sliced differently

About Chromosome Evil

The closest matches to Chromosome Evil: Chromosome Evil 2, Welcome Back, Commander, Flesh Eaters, Last Train Home, and They Are Billions. Ranked by imho.run from Steam co-play data, shared tags and reviews.

If Chromosome Evil is your kind of game, the closest matches are Chromosome Evil 2, Welcome Back, Commander and Flesh Eaters — picked from the ranked list below. Reviewers describe it as atmospheric, dark and grim, and single out its character and equipment upgrades and limited ammo. Each pick is ranked by what players of this game also play, shared genres and tags, and review-mined similarity — not a generic popularity list.

About Chromosome Evil: Dive deep into this Lovecraft-inspired RTS survival. Assemble your team using different classes, skills, and weaponry. It's up to your squad to survive the onslaught of nightmares that are surely coming your way. Will you find the source of the darkness?

Is Chromosome Evil worth buying?

  • 82% of 221 Steam reviews are positive.
  • We don't track this game's daily reviews yet, so this is the all-time picture.
  • On sale: 40% off, now $8.99 (checked Nov 7).
  • People who recommend it had played a median of 13 h when they wrote their review.
  • Steam Deck Playable: works, with some rough edges.

What fans praise · Themes mined from positive reviews

Top critical reviews

The most up-voted negative English reviews in our sample, quoted as written.

“Huh, NO SAVE for hard mode? Seriously, I understand "no save for cheating", but "no save for game quitting"? Just one go whole game, or waste your 'resource' and 'turn'? This is so ridiculous.”
2 h played
More negative reviews on Steam ↗

People who play it also play: Chromosome Evil 2, Welcome Back, Commander, Flesh Eaters

How this verdict works →

Frequently asked about Chromosome Evil

Can I run it?

Does Chromosome Evil run on Steam Deck?

Chromosome Evil is rated Playable on Steam Deck — it runs, but expect some manual adjustments (control remapping, text size, or graphics settings) for the best experience.

How much does Chromosome Evil cost?

Chromosome Evil is listed on Steam at 8.99 USD (current store price; Steam sales may reduce this temporarily).

What games are most similar to Chromosome Evil?

Based on Steam play patterns and shared genres/tags, the games most often recommended alongside Chromosome Evil are Chromosome Evil 2, Welcome Back, Commander, Flesh Eaters.

Who developed Chromosome Evil?

Chromosome Evil was developed by S.C. 16 BIT NIGHTS S.R.L..