IMHO.

Games like Chromosome Evil 2

If Chromosome Evil 2 is your kind of game, the closest matches are Aliens: Dark Descent, Monsters In The Shadows and Project: Aurora — picked from the ranked list below. Reviewers single out its atmospheric, challenging and dark. Each pick is ranked by what players of this game also play, shared genres and tags, and review-mined similarity — not a generic popularity list.

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About Chromosome Evil 2: Dive deep into this Lovecraft-inspired RTS survival for a second time. Assemble your strike team and manage your convoy. It's up to you to survive the onslaught of nightmares that are surely coming your way. Will you find the source of the darkness?

2024StrategyRPG19.99 USDDeck PlayableWindowsby S.C. 16 BIT NIGHTS S.R.L., dovganovskiy
Chromosome Evil 2 — Steam game cover
Players highlight
Ammo scarcity forces melee combatDeep squad management with persistent progressionDeep tactical squad management with real time combatAtmosphericChallengingDark

Players who liked Chromosome Evil 2 also play

Steam players who put hours into Chromosome Evil 2 also tend to own these titles — a signal called collaborative filtering. imho.run cross-references millions of library ownership patterns to surface games whose real audiences overlap, regardless of whether their genre tags match.

  1. Aliens: Dark Descent

    WHY THIS

    Shares resource management and an atmospheric mood with Chromosome Evil 2.

    Top pick for Chromosome Evil 2 fans by collaborative filtering across millions of Steam libraries. Shares Strategy with Chromosome Evil 2.

    Drop into the gripping journey of Aliens: Dark Descent, a squad-based, single-player action game in the iconic Alien franchise. Lead your soldiers in real-time to stop a new and terrifying kind of Xenomorph outbreak on Planet Lethe.

    2023ActionStrategy39.99 USDDeck PlayableSteam ↗
  2. Monsters In The Shadows

    WHY THIS

    Second-strongest match for Chromosome Evil 2 fans by collaborative filtering across millions of Steam libraries. Shares Strategy with Chromosome Evil 2.

    Low-poly horror fps survival shooter game. Kill monsters hidden within the walls of an abandoned city.

    2022ActionStrategyIndieFreeDeck PlayableSteam ↗
  3. Project: Aurora

    WHY THIS

    Third-strongest match for Chromosome Evil 2 fans by collaborative filtering across millions of Steam libraries. Shares Strategy and RPG with Chromosome Evil 2.

    Aurora isn't as desolate as it seems. Survive amidst storms, lost technologies, and remnants of a vanished civilization—before you become part of them.Aurora is not as abandoned as it seems. As in classic sci-fi, discovering its secret means confronting the depths of cosmic horror.

    2026StrategyIndieAdventure13.99 USDDeck PlayableSteam ↗
  4. Darkwood

    WHY THIS

    Shares an atmospheric mood with Chromosome Evil 2.

    Ranked #4 for Chromosome Evil 2 fans by collaborative filtering across millions of Steam libraries. Shares Strategy and RPG with Chromosome Evil 2.

    Darkwood - a new perspective on survival horror. Scavenge and explore a rich, ever-changing free-roam world by day, then hunker down in your hideout and pray for the morning light.

    2017ActionStrategyAdventure14.99 USDDeck VerifiedSteam ↗
  5. Zafehouse Diaries 2

    WHY THIS

    Shares resource management and an atmospheric mood with Chromosome Evil 2.

    Ranked #5 for Chromosome Evil 2 fans by collaborative filtering across millions of Steam libraries. Shares Strategy and RPG with Chromosome Evil 2.

    Zafehouse Diaries 2 is a game of survival, exploration and relationships. Every hour, designate tasks for your handful of characters - each with their own skills, motivations and prejudices - and try to outlast the zombie apocalypse.

    2017StrategyIndieRPG6.99 USDSteam ↗
  6. Expedition: Shadow World

    WHY THIS

    Ranked #6 for Chromosome Evil 2 fans by collaborative filtering across millions of Steam libraries. Shares Strategy with Chromosome Evil 2.

    Expedition: Shadow World is a tactical game about an expedition sent to a distant planet to extract energy resources. Command a group of five troopers in real-time battles with a tactical pause and discover the mystery of the planet.

    2025StrategyIndie8.79 USDSteam ↗
  7. Xenoids

    WHY THIS

    Ranked #7 for Chromosome Evil 2 fans by collaborative filtering across millions of Steam libraries.

    Xenoids is a survival horror game where you have to face a hostile life form in the confined space of a spaceship.

    2024ActionEarly Access9.99 USDSteam ↗
  8. Chromosome Evil

    WHY THIS

    Shares resource management and an atmospheric mood with Chromosome Evil 2.

    Ranked #8 for Chromosome Evil 2 fans by collaborative filtering across millions of Steam libraries. Shares Strategy with Chromosome Evil 2.

    Dive deep into this Lovecraft-inspired RTS survival. Assemble your team using different classes, skills, and weaponry. It's up to your squad to survive the onslaught of nightmares that are surely coming your way. Will you find the source of the darkness?

    2022Strategy14.99 USDDeck PlayableSteam ↗

Reviewers mention these as similar to Chromosome Evil 2

Surfaced from review text: when other players write 'if you liked X, try Y', we catch the name and resolve it back to a Steam game.

  1. Strain Tactics

    WHY THIS

    Shares tactical positioning and an atmospheric mood with Chromosome Evil 2.

    Reviewers of Chromosome Evil 2 cross-mention this title as a similar play. Shares Strategy with Chromosome Evil 2.

    Strain Tactics is a real-time-with-pause tactical game, where you command a squad of soldiers to liberate earth from an alien infestation. Using your helibase, deploy your custom squad and provide air support. Remember to keep your crew sane and motivated while staying clear of alien contamination!

    2017ActionStrategyIndie14.99 USDSteam ↗
  2. Xenonauts

    WHY THIS

    Shares an atmospheric mood with Chromosome Evil 2.

    Reviewers of Chromosome Evil 2 cross-mention this title as a similar play. Shares Strategy with Chromosome Evil 2.

    Xenonauts is a strategy game in which you control a multi-national military organisation defending a Cold War-era Earth from alien invasion, using small squads of persistent soldiers to eliminate the extraterrestrials and recover their technology in turn-based ground combat.

    2014StrategyIndieSimulation24.99 USDSteam ↗
  3. Killing Floor

    WHY THIS

    Shares a grim mood with Chromosome Evil 2.

    Reviewers of Chromosome Evil 2 cross-mention this title as a similar play.

    6-player co-op survival horror at its finest! Free updates, free special events and a ridiculous amount of fun!

    2009Action19.99 USDDeck PlayableSteam ↗
  4. Xenonauts 2

    WHY THIS

    Shares tactical combat and a challenging mood with Chromosome Evil 2.

    Reviewers of Chromosome Evil 2 cross-mention this title as a similar play. Shares Strategy and RPG with Chromosome Evil 2.

    Wage a global war of resistance against an alien invasion. Command turn-based tactical battles, build a network of covert bases, directly control your fighter wings, and achieve strategic victory in a simulation of asymmetric warfare against a technologically superior foe.

    2026StrategySimulationRPG39.99 USDDeck PlayableSteam ↗
  5. SAS: Zombie Assault 4

    WHY THIS

    Shares a tense mood with Chromosome Evil 2.

    Reviewers of Chromosome Evil 2 cross-mention this title as a similar play. Shares RPG with Chromosome Evil 2.

    Purge the undead! Intense action-shooter with deep rpg elements, including upgradeable guns and armor, unique class skills, and class special abilities. Entire game can be played single player or as a 4-player online co-op game, including PvP events like Last Man Standing.

    2017ActionRPGFree To PlayFreeDeck VerifiedSteam ↗
  6. XCOM® 2

    WHY THIS

    Shares an atmospheric mood with Chromosome Evil 2.

    Reviewers of Chromosome Evil 2 cross-mention this title as a similar play. Shares Strategy with Chromosome Evil 2.

    XCOM 2 is the sequel to XCOM: Enemy Unknown, the 2012 award-winning strategy game of the year. Earth has changed and is now under alien rule. Facing impossible odds you must rebuild XCOM, and ignite a global resistance to reclaim our world and save humanity.

    2016Strategy2.99 USDDeck PlayableSteam ↗
  7. The Bureau: XCOM Declassified

    WHY THIS

    Reviewers of Chromosome Evil 2 cross-mention this title as a similar play.

    The year is 1962 and the Cold War has the nation gripped by fear.  A top-secret government unit called The Bureau begins investigating a series of mysterious attacks by an enemy more powerful than communism.

    2013Action19.99 USDDeck VerifiedSteam ↗

Cheaper alternatives

Games in the same vein priced at least 40% below Chromosome Evil 2 at current Steam store prices.

  1. Terraria

    WHY THIS

    Priced ~50% under Chromosome Evil 2 on Steam right now. Shares RPG with Chromosome Evil 2.

    Dig, fight, explore, build! Nothing is impossible in this action-packed adventure game. Four Pack also available!

    2011ActionIndieAdventure9.99 USDDeck VerifiedSteam ↗
  2. Fallout: New Vegas

    WHY THIS

    Priced ~50% under Chromosome Evil 2 on Steam right now. Shares RPG with Chromosome Evil 2.

    Welcome to Vegas. New Vegas. Enjoy your stay!

    2010ActionRPG9.99 USDDeck PlayableSteam ↗
  3. Undertale

    WHY THIS

    Priced ~50% under Chromosome Evil 2 on Steam right now. Shares RPG with Chromosome Evil 2.

    UNDERTALE! The RPG game where you don't have to destroy anyone.

    2015IndieRPG9.99 USDDeck PlayableSteam ↗
  4. Vampire Survivors

    WHY THIS

    Priced ~75% under Chromosome Evil 2 on Steam right now. Shares RPG with Chromosome Evil 2.

    Mow down thousands of night creatures and survive until dawn! Vampire Survivors is a gothic horror casual game with rogue-lite elements, where your choices can allow you to quickly snowball against the hundreds of monsters that get thrown at you. Be the bullet hell!

    2022ActionIndieRPG4.99 USDDeck VerifiedSteam ↗
  5. Sid Meier's Civilization® V

    WHY THIS

    Priced ~63% under Chromosome Evil 2 on Steam right now. Shares Strategy with Chromosome Evil 2.

    Create, discover, and download new player-created maps, scenarios, interfaces, and more!

    2010Strategy7.49 USDDeck PlayableSteam ↗
  6. Slay the Spire

    WHY THIS

    Priced ~69% under Chromosome Evil 2 on Steam right now. Shares Strategy with Chromosome Evil 2.

    We fused card games and roguelikes together to make the best single player deckbuilder we could. Craft a unique deck, encounter bizarre creatures, discover relics of immense power, and Slay the Spire!

    2019StrategyIndie6.24 USDDeck VerifiedSteam ↗
  7. Inscryption

    WHY THIS

    Priced ~60% under Chromosome Evil 2 on Steam right now. Shares Strategy with Chromosome Evil 2.

    Inscryption is an inky black card-based odyssey that blends the deckbuilding roguelike, escape-room style puzzles, and psychological horror into a blood-laced smoothie. Darker still are the secrets inscrybed upon the cards...

    2021StrategyIndieAdventure7.99 USDDeck PlayableSteam ↗
  8. Cookie Clicker

    WHY THIS

    Priced ~75% under Chromosome Evil 2 on Steam right now. Shares Strategy with Chromosome Evil 2.

    An idle game about making cookies! Originally released in 2013 on the web, and actively developed since then. This is the official version for Steam.

    2021StrategyIndieSimulation4.99 USDDeck PlayableSteam ↗

Free alternatives

Free-to-play games that recommended players of this title also tend to enjoy.

  1. Ultimate Custom Night

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it.

    Welcome to the ultimate FNAF mashup, featuring 50 selectable characters and custom difficulties!

    2018ActionIndieFree To PlayFreeSteam ↗
  2. Our Life: Beginnings & Always

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it.

    A twenty-dollar bill, four summers, fifteen years, and a one of a kind life. Create an experience that’s all your own in this near-fully customizable visual novel where you grow from childhood to adulthood with the lonely boy next door.

    2020IndieFree To PlayCasualFreeSteam ↗
  3. Grimm's Hollow

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares RPG with Chromosome Evil 2.

    A spooky, freeware RPG where you search the afterlife for your brother. Reap ghosts with your scythe, explore haunted caves, and eat ghostly treats on your journey through death.

    2019IndieAdventureRPGFreeDeck PlayableSteam ↗
  4. Magic Archery

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares RPG with Chromosome Evil 2.

    Train a commoner to become the greatest archer in this short incremental game! Increase your stats, gather wealth from quests, buy upgrades, and infuse your arrows with magic.

    2024IndieSimulationRPGFreeDeck PlayableSteam ↗
  5. Eternal Senia

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares RPG with Chromosome Evil 2.

    Thoughts and expectations ARPG

    2015ActionIndieRPGFreeDeck PlayableSteam ↗
  6. Paper Lily - Chapter 1

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares RPG with Chromosome Evil 2.

    Paper Lily is an RPG horror game in which you can solve puzzles in different ways. Explore a hidden world, meet strange characters, and guide Lacie as she attempts to find answers about her unusual condition.

    2024IndieAdventureRPGFreeDeck VerifiedSteam ↗
  7. The Lab

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it.

    Welcome to The Lab, a compilation of Valve’s room-scale VR experiments set in a pocket universe within Aperture Science. Fix a robot, defend a castle, adopt a mechanical dog, and more. Still not sold? It’s free!

    2016Free To PlayFreeSteam ↗
  8. Project Kat - Paper Lily Prologue

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares RPG with Chromosome Evil 2.

    Project Kat is a short, unconventional RPG horror game in which there is always another way. Solve puzzles, make friends (or not), and guide Kat as she attempts to uncover the mystery behind a strange golden letter.

    2021IndieAdventureRPGFreeDeck VerifiedSteam ↗

More from S.C. 16 BIT NIGHTS S.R.L.

Other recommendable Steam games by S.C. 16 BIT NIGHTS S.R.L., ranked by review count so the studio's hits land first.

  1. Flesh Eaters

    WHY THIS

    Shares resource management and an atmospheric mood with Chromosome Evil 2.

    Another title from S.C. 16 BIT NIGHTS S.R.L., the studio behind Chromosome Evil 2.

    Flesh Eaters is retro style single player RTS zombie survival game with resource gathering and crafting. Zombies are everywhere! You must gather resources to build barricades, upgrade weapons and armour and explore the city under the siege of the dead

    2016ActionIndieAdventure4.99 USDSteam ↗
  2. Chromosome Evil

    WHY THIS

    Shares resource management and an atmospheric mood with Chromosome Evil 2.

    Another title from S.C. 16 BIT NIGHTS S.R.L., the studio behind Chromosome Evil 2. Shares Strategy with Chromosome Evil 2.

    Dive deep into this Lovecraft-inspired RTS survival. Assemble your team using different classes, skills, and weaponry. It's up to your squad to survive the onslaught of nightmares that are surely coming your way. Will you find the source of the darkness?

    2022Strategy14.99 USDDeck PlayableSteam ↗
  3. Welcome Back, Commander

    WHY THIS

    Shares stealth, permadeath and atmospheric with Chromosome Evil 2.

    Another title from S.C. 16 BIT NIGHTS S.R.L., the studio behind Chromosome Evil 2. Shares Strategy with Chromosome Evil 2.

    Commander, your strike team is to dive deep into the contaminated city of Sun Stone and get some answers before the mysterious deadly plague spreads . Good luck Commander!

    2025StrategySimulation9.99 USDDeck PlayableSteam ↗
  4. TAURONOS

    WHY THIS

    Shares permadeath and an atmospheric mood with Chromosome Evil 2.

    Another title from S.C. 16 BIT NIGHTS S.R.L., the studio behind Chromosome Evil 2.

    Trapped inside an ancient labyrinth, chased by the mythical Minotaur. Will you reach the center? And if so, what will you discover about yourself there, in the dark?

    2017IndieAdventure4.99 USDDeck PlayableSteam ↗
  5. Desolated District

    WHY THIS

    Another title from S.C. 16 BIT NIGHTS S.R.L., the studio behind Chromosome Evil 2.

    Desolated District is an Open-World Survival Crafting game set in a post-apocalyptic dystopia. Scavenge for resources, craft essential tools, build your base and battle deadly threats as you explore a sprawling, decaying city inspired by the Kowloon Walled City.

    2025ActionAdventure6.74 USDSteam ↗

Frequently asked about Chromosome Evil 2

Does Chromosome Evil 2 run on Steam Deck?
Chromosome Evil 2 is rated Playable on Steam Deck — it runs, but expect some manual adjustments (control remapping, text size, or graphics settings) for the best experience.
How much does Chromosome Evil 2 cost?
Chromosome Evil 2 is listed on Steam at 19.99 USD (current store price; Steam sales may reduce this temporarily).
What games are most similar to Chromosome Evil 2?
Based on Steam play patterns and shared genres/tags, the games most often recommended alongside Chromosome Evil 2 are Aliens: Dark Descent, Monsters In The Shadows, Project: Aurora.
Who developed Chromosome Evil 2?
Chromosome Evil 2 was developed by S.C. 16 BIT NIGHTS S.R.L., dovganovskiy and published by S.C. 16 BIT NIGHTS S.R.L..

imho.run ranks Steam game alternatives using a mix of collaborative filtering (ALS / iALS / EASE / LightGCN), content scoring over genres, categories, Steam tags, developers, and publishers, plus AI-extracted vibes mined from review text. The page above is generated in seed mode anchored on Chromosome Evil 2.

For library-aware picks tuned to your specific taste, sign in with Steam on the home page.

36 Games Like Chromosome Evil 2 — Ranked for 2026 · imho.run