Rank 01Why this
Shares resource management with Chromosome Evil 2.
- $8.99 (Price checked Nov 7)
- Deck Playable
- 2022
Games like Chromosome Evil 2
- 17 games
- Updated May 5, 2026
Players who liked Chromosome Evil 2 also play
The closest matches to Chromosome Evil 2: Chromosome Evil, Welcome Back, Commander, Aliens: Dark Descent, Dead in Antares, and Cataclysm: Dark Days Ahead. Ranked by imho.run from Steam co-play data, shared tags and reviews.
- Rank 01
Rank 02Why this
Shares stealth and tactical positioning with Chromosome Evil 2.
- $7.79 (Price checked Nov 7)
- Deck Playable
- 2025
Rank 03Why this
Also Aliens and RTS, like Chromosome Evil 2.
- $11.99 (Price checked Nov 7)
- Deck Playable
- 2023
Rank 04 
Dead in Antares
Why this: Shares tactical combat and base building with Chromosome Evil 2.
Rank 05 
Cataclysm: Dark Days Ahead
Why this: Shares resource scarcity and permadeath with Chromosome Evil 2.
Rank 06 
Don't Starve Together
Why this: Also Survival Horror and Crafting, like Chromosome Evil 2.
Rank 07 
Phoenix Point
Why this: Shares procedural enemy evolution and resource management with Chromosome Evil 2.
Rank 08 
The full ranked list: top 24 games like Chromosome Evil 2
Best match first, as plain text. The same list for AI assistants:
- 1
- 2Welcome Back, Commander
Shares stealth and tactical positioning with Chromosome Evil 2.
- 83% of 116 reviews
- 3
- 4
- 5Cataclysm: Dark Days Ahead
Shares resource scarcity and permadeath with Chromosome Evil 2.
- 92% of 312 reviews
- 6Don't Starve Together
Also Survival Horror and Crafting, like Chromosome Evil 2.
- 96% of 80,691 reviews
- 7Phoenix Point
Shares procedural enemy evolution and resource management with Chromosome Evil 2.
- 71% of 3,001 reviews
- 8
- 9Cataclysm: The Last Generation
Shares permadeath and inventory management with Chromosome Evil 2.
- 93% of 183 reviews
- 10
- 11XCOM: Enemy Unknown
Shares squad management and base building with Chromosome Evil 2.
- 93% of 24,805 reviews
- 12
- 13ARK: Survival Ascended
Shares resource scarcity and vehicle customization with Chromosome Evil 2.
- 60% of 53,496 reviews
- 14
- 15The Forest
Shares base building and resource management with Chromosome Evil 2.
- 95% of 175,474 reviews
- 16Last Hope Bunker: Zombie Survival
Shares stealth and base building with Chromosome Evil 2.
- 77% of 86 reviews
- 17
- 18
- 19
- 20
- 21Tenebris: Terra Incognita
Shares squad management and tactical combat with Chromosome Evil 2.
- 82% of 491 reviews
- 22
- 23
- 24
- Released: 2024
- Developer: S.C. 16 BIT NIGHTS S.R.L., dovganovskiy
- Price: $1.99−90%checked Nov 7
- Steam Deck: Deck Playable
- 88% of 105 reviews
- Genres: Strategy, RPG
- Platforms: Windows
Players highlight
- Ammo scarcity forces melee combat
- Deep squad management with persistent progression
- Deep tactical squad management with real time combat
- Atmospheric
- Challenging
- Dark
More games like Chromosome Evil 2, sliced differently
Reviewers mention these as similar to Chromosome Evil 2
Surfaced from review text: when other players write 'if you liked X, try Y', we catch the name and resolve it back to a Steam game.
Strain Tactics
Why this: Shares tactical positioning with Chromosome Evil 2.
Xenonauts
Why this: Same atmospheric mood as Chromosome Evil 2.
Xenonauts 2
Why this: Shares tactical combat with Chromosome Evil 2.
SAS: Zombie Assault 4
Why this: Same tense mood as Chromosome Evil 2.
More from S.C. 16 BIT NIGHTS S.R.L.
Other recommendable Steam games by S.C. 16 BIT NIGHTS S.R.L., ranked by review count so the studio's hits land first.
Flesh Eaters
Why this: Shares resource management with Chromosome Evil 2.
TAURONOS
Why this: Shares permadeath with Chromosome Evil 2.
About Chromosome Evil 2
The closest matches to Chromosome Evil 2: Chromosome Evil, Welcome Back, Commander, Aliens: Dark Descent, Dead in Antares, and Cataclysm: Dark Days Ahead. Ranked by imho.run from Steam co-play data, shared tags and reviews.
If Chromosome Evil 2 is your kind of game, the closest matches are Chromosome Evil, Welcome Back, Commander and Aliens: Dark Descent — picked from the ranked list below. Reviewers describe it as atmospheric, challenging and dark, and single out its base building and campaign progression. Each pick is ranked by what players of this game also play, shared genres and tags, and review-mined similarity — not a generic popularity list.
About Chromosome Evil 2: Dive deep into this Lovecraft-inspired RTS survival for a second time. Assemble your strike team and manage your convoy. It's up to you to survive the onslaught of nightmares that are surely coming your way. Will you find the source of the darkness?
Is Chromosome Evil 2 worth buying?
Players recommend it
A summary of what players say, not a promise you'll like it. Every signal is listed below.
- 88% of 105 Steam reviews are positive.
- We don't track this game's daily reviews yet, so this is the all-time picture.
- On sale: 90% off, now $1.99 (checked Nov 7).
- People who recommend it had played a median of 25 h when they wrote their review.
- Steam Deck Playable: works, with some rough edges.
What fans praise · Themes mined from positive reviews
- Ammo scarcity forces melee combat
- Deep squad management with persistent progression
- Deep tactical squad management with real time combat
- Evolving enemies that change tactics as you progress
Top critical reviews
The most up-voted negative English reviews in our sample, quoted as written.
“This may be my first negative review in a game... I'm getting old... The game is playable. and the story is... ok The main issue, for me is the transition from mission to mission. It does not allow you to change configuration before…”
People who play it also play: Chromosome Evil, Welcome Back, Commander, Aliens: Dark Descent
Frequently asked about Chromosome Evil 2
Can I run it?
Does Chromosome Evil 2 run on Steam Deck?
Chromosome Evil 2 is rated Playable on Steam Deck — it runs, but expect some manual adjustments (control remapping, text size, or graphics settings) for the best experience.
How much does Chromosome Evil 2 cost?
Chromosome Evil 2 is listed on Steam at 1.99 USD (current store price; Steam sales may reduce this temporarily).
What games are most similar to Chromosome Evil 2?
Based on Steam play patterns and shared genres/tags, the games most often recommended alongside Chromosome Evil 2 are Chromosome Evil, Welcome Back, Commander, Aliens: Dark Descent.
Who developed Chromosome Evil 2?
Chromosome Evil 2 was developed by S.C. 16 BIT NIGHTS S.R.L., dovganovskiy and published by S.C. 16 BIT NIGHTS S.R.L..